Circadian oscillators are networks of biochemical feedback loops that generate 24-hour
rhythms in organisms from bacteria to animals. These periodic rhythms result from a …

Recent studies have unveiled the molecular machinery responsible for the biological clock
in cyanobacteria and found that it exerts pervasive control over cellular processes including …

Cyanobacteria have a robust circadian oscillator, known as the Kai system. Reconstituted
from the purified protein components KaiC, KaiB, and KaiA, it can tick autonomously in the …

Circadian clocks generate slow and ordered cellular dynamics but consist of fast-moving bio-
macromolecules; consequently, the origins of the overall slowness remain unclear. We …

The circadian oscillator of the cyanobacterium Synechococcus elongatus is composed of
only three proteins, KaiA, KaiB, and KaiC, which, together with ATP, can generate a self …

Circadian rhythms play an essential part in many biological processes, and only three
prokaryotic proteins are required to constitute a true post-translational circadian oscillator …

Biological processes are typically actuated by dynamic multi-subunit molecular complexes.
However, interactions between subunits, which govern the functions of these complexes, are …

Synchronization of the circadian clock in cyanobacteria with the day/night cycle proceeds
without an obvious photoreceptor, leaving open the question of its specific mechanism. The …

Genetically encoded biological clocks are found broadly throughout eukaryotes and in
cyanobacteria, where they generate circadian (about a day) rhythms that allow organisms to …

A biochemical oscillator can be reconstituted in vitro with three purified proteins, that
displays the salient properties of circadian (daily) rhythms, including self-sustained 24-h …