Minireview: Pref-1: role in adipogenesis and mesenchymal cell fate

HS Sul - Molecular endocrinology, 2009 - academic.oup.com
Abstract Preadipocyte factor-1 [Pref-1; also called Dlk1 (Delta-like protein 1)] is made as an
epidermal growth factor-repeat containing transmembrane protein that produces a …

The role of delta-like non-canonical Notch ligand 1 (DLK1) in cancer

JFH Pittaway, C Lipsos, K Mariniello… - Endocrine-Related …, 2021 - erc.bioscientifica.com
Delta-like non-canonical Notch ligand 1 (DLK1) is a cleavable single-pass transmembrane
protein and a member of the Notch/Delta/Serrate family. It is paternally expressed and …

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes

C Wallace, DJ Smyth, M Maisuria-Armer, NM Walker… - Nature …, 2010 - nature.com
Genome-wide association (GWA) studies to map common disease susceptibility loci have
been hugely successful, with over 300 reproducibly associated loci reported to date …

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

C Flotho, R Claus, C Batz, M Schneider, I Sandrock… - Leukemia, 2009 - nature.com
The three DNA methyltransferase (DNMT)-inhibiting cytosine nucleoside analogues,
azacitidine, decitabine and zebularine, which are currently studied as nonintensive therapy …

[PDF][PDF] The effect of Cannabis seed on DLK1 gene expression in heart tissue of Kermani lambs

SAA Jafari Ahmadabadi, H Askari-Hemmat… - Agricultural …, 2023 - sid.ir
Objective Cannabis seeds have high amounts of crude protein and energy, so they can
better resist the microbial digestion of the rumen and pass through the intact rumen to a …

[HTML][HTML] Possible roles of DLK1 in the Notch pathway during development and disease

FA Falix, DC Aronson, WH Lamers… - Biochimica et Biophysica …, 2012 - Elsevier
The Delta-Notch pathway is an evolutionarily conserved signaling pathway which controls a
broad range of developmental processes including cell fate determination, terminal …

Deletion of delta-like 1 homologue accelerates fibroblast–myofibroblast differentiation and induces myocardial fibrosis

P Rodriguez, Y Sassi, L Troncone… - European heart …, 2019 - academic.oup.com
Aims Myocardial fibrosis is associated with profound changes in ventricular architecture and
geometry, resulting in diminished cardiac function. There is currently no information on the …

Specific small nucleolar RNA expression profiles in acute leukemia

W Valleron, E Laprevotte, EF Gautier, C Quelen… - Leukemia, 2012 - nature.com
Apart from microRNAs, little is known about the regulation of expression of non-coding
RNAs in cancer. We investigated whether small nucleolar RNAs (snoRNAs) accumulation …

Skeletal (stromal) stem cells: an update on intracellular signaling pathways controlling osteoblast differentiation

BM Abdallah, A Jafari, W Zaher, W Qiu, M Kassem - Bone, 2015 - Elsevier
Skeletal (marrow stromal) stem cells (BMSCs) are a group of multipotent cells that reside in
the bone marrow stroma and can differentiate into osteoblasts, chondrocytes and …

The EGF-like protein dlk1 inhibits notch signaling and potentiates adipogenesis of mesenchymal cells

ML Nueda, V Baladrón, B Sánchez-Solana… - Journal of molecular …, 2007 - Elsevier
The EGF-like homeotic gene Dlk1 appears to function as an inhibitor of adipogenesis.
Overexpression of Dlk1 prevents adipogenesis of 3T3-L1 cells. Dlk1-deficient mice are …