Clostridium difficile is a bacterial pathogen that is the leading cause of nosocomial antibiotic-
associated diarrhea and pseudomembranous colitis worldwide. The incidence, severity …

The gastrointestinal microbiome plays a pivotal role in physiological homeostasis of the
intestine as well as in the pathophysiology of diseases including inflammatory bowel …

Clostridium difficile infection (CDI) has significant clinical impact especially on the elderly
and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly …

Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is
increasing the susceptibility of cells to death. Cancer cells have developed a capability of …

Inflammatory bowel disease (IBD) is a global disease that is in increasing incidence. The
gut, which contains the largest amount of lymphoid tissue in the human body, as well as a …

The gut microbiota is currently considered an external organ of the human body that
provides important mechanisms of metabolic regulation and protection. The gut microbiota …

Clostridium difficile is a toxin-producing bacterium that is a frequent cause of hospital-
acquired and antibiotic-associated diarrhea. The incidence, severity, and costs associated …

Clostridia produce the highest number of toxins of any type of bacteria and are involved in
severe diseases in humans and other animals. Most of the clostridial toxins are pore-forming …

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract with unknown etiology. The pathogenesis of IBD results from immune responses to …

Alzheimer's disease and Parkinson's disease are neurodegenerative disorders
characterised by the misfolding of proteins into soluble prefibrillar aggregates. These …