Chaperone-based therapeutic target innovation: Heat shock protein 70 (HSP70) for Type 2 diabetes mellitus

WRW Mulyani, MID Sanjiwani, Sandra… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is still a global health problem. Current T2DM treatments
are limited to curing the symptoms and have not been able to restore insulin sensitivity in …

The role of heat shock proteins (HSPs) in type 2 diabetes mellitus pathophysiology

A Esmaeilzadeh, V Mohammadi, R Elahi… - Journal of Diabetes and …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by sustained
hyperglycemia caused by impaired insulin signaling and secretion. Metabolic stress, caused …

Grinding process for the production of nanofibrillated cellulose based on unbleached and bleached bamboo organosolv pulp

VC Correia, V dos Santos, M Sain, SF Santos, AL Leao… - Cellulose, 2016 - Springer
Nanofibrillated cellulose (NFC) is a type of nanomaterial based on renewable resources and
produced by mechanical disintegration without chemicals. NFC is a potential reinforcing …

Hsp60 in skeletal muscle fiber biogenesis and homeostasis: From physical exercise to skeletal muscle pathology

A Marino Gammazza, F Macaluso, V Di Felice… - Cells, 2018 - mdpi.com
Hsp60 is a molecular chaperone classically described as a mitochondrial protein with
multiple roles in health and disease, participating to the maintenance of protein …

[HTML][HTML] HSP70 as a biomarker of the thin threshold between benefit and injury due to physical exercise when exposed to air pollution

LC Costa-Beber, TG Heck, PBG Fiorin… - Cell Stress and …, 2021 - Elsevier
Physical exercise has acute and chronic effects on inflammatory balance, metabolic
regulation, and redox status. Exercise-induced adaptations are mediated by enhanced 70 …

Inflammatory mechanisms associated with skeletal muscle sequelae after stroke: role of physical exercise

HJ Coelho Junior, BB Gambassi… - Mediators of …, 2016 - Wiley Online Library
Inflammatory markers are increased systematically and locally (eg, skeletal muscle) in stroke
patients. Besides being associated with cardiovascular risk factors, proinflammatory …

The impact of age and frailty on skeletal muscle autophagy markers and specific strength: A cross-sectional comparison

SN Aas, H Hamarsland, KT Cumming… - Experimental …, 2019 - Elsevier
Aging is associated with reduced specific strength, defined as strength normalized to the
cross-sectional area of a given muscle or muscle group. Dysregulated autophagy, impairing …

A pilot study on the relationship between Lactobacillus, Bifidibactrium counts and inflammatory factors following exercise training

MS Mahdieh, J Maryam, B Bita, F Neda… - … of physiology and …, 2023 - Taylor & Francis
Background The current pilot study was carried out to examine the effect of aerobic exercise
on Lactobacillus and Bifidobacterium as a function of weight loss and cytokine changes in …

Chronic heat treatment positively impacts metabolic profile of ovariectomized rats: association with heat shock response pathways

YPS Lissarassa, CF Vincensi, LC Costa-Beber… - Cell Stress and …, 2020 - Springer
Low estrogen levels may predispose women to increased bodyweight and dyslipidemia.
Previous studies from our laboratory suggest an involvement of depressed heat shock …

Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training

JP Ahtiainen, S Lensu, I Ruotsalainen… - Experimental …, 2018 - Wiley Online Library
New Findings What is the central question of this study? Can phenotypic traits associated
with low response to one mode of training be extrapolated to other exercise‐inducible …