Cholesterol modulates the bilayer structure of biological membranes in multiple ways. It
changes the fluidity, thickness, compressibility, water penetration and intrinsic curvature of …

Diverse membrane fusion reactions in biology involve close contact between two lipid
bilayers, followed by the local distortion of the individual bilayers and reformation into a …

Arginine-rich cell-penetrating peptides do not enter cells by directly passing through a lipid
membrane; they instead passively enter vesicles and live cells by inducing membrane …

Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique
biophysical properties: a small headgroup; negative charge; and a phosphomonoester …

Severe vitamin E deficiency results in lethal myopathy in animal models. Membrane repair is
an important myocyte response to plasma membrane disruption injury as when repair fails …

Lipid mediators participate in signal transduction pathways, proliferation, apoptosis, and
membrane trafficking in the cell. Lipids are highly complex and diverse owing to the various …

We have used X-ray diffraction on the rhombohedral phospholipid phase to reconstruct stalk
structures in different pure lipids and lipid mixtures with unprecedented resolution, enabling …

Cholesterol and sphingolipids are abundant in neuronal membranes, where they help the
organisation of the membrane microdomains involved in major roles such as axonal and …

Ions are ubiquitous in nature. They play a key role for many biological processes on the
molecular scale, from molecular interactions, to mechanical properties, to folding, to self …

The impact of cholesterol on the structure and function of membrane proteins was
recognized several decades ago, but the molecular mechanisms underlying these effects …