Mycotoxins are secondary metabolites produced by certain filamentous fungi, which can be
produced 2.1. The Aspergillus mycotoxins in foods as a result of fungal growth (Table 1) …

Affatoxins, a group of polyketide-derived furanocoumarins (Fig. 1), are the most toxic and
carcinogenic compounds among the known mycotoxins. Among the at least 16 structurally …

Secondary metabolites, or biochemical indicators of fungal development, are of intense
interest to humankind due to their pharmaceutical and/or toxic properties. We present here a …

Traditional molecular techniques have been used in research in discovering the genes and
enzymes that are involved in aflatoxin formation and genetic regulation. We cloned most, if …

Several species of the genus Fusarium and related fungi produce trichothecenes which are
sesquiterpenoid epoxides that act as potent inhibitors of eukaryotic protein synthesis …

Sterigmatocystin (ST) and the aflatoxins (AFs), related fungal secondary metabolites, are
among the most toxic, mutagenic, and carcinogenic natural products known. The ST …

▪ Abstract Aflatoxins are the most thoroughly studied mycotoxins. Elegant early research on
the biosynthetic scheme of the pathway has allowed a molecular characterization of …

Trichothecenes and fumonisins are mycotoxins produced by Fusarium, a filamentous fungus
that can cause disease in barley, maize, rice, wheat, and some other crop plants. Research …

▪ Abstract Melanins are darkly pigmented polymers that protect organisms against
environmental stress. Even when not directly involved in pathogenesis, fungal melanin is …

The genus Aspergillus is renowned for its ability to produce a myriad of bioactive secondary
metabolites. Although the propensity of biosynthetic genes to form contiguous clusters …