Energy metabolism in mammalian sperm motility

A Amaral - WIREs mechanisms of disease, 2022 - Wiley Online Library
Mammalian sperm, the only cells that achieve their purpose outside their organism of origin,
have to swim vigorously within the female reproductive tract to reach an oocyte. Flagellar …

Sperm metabolomics through nuclear magnetic resonance spectroscopy

M Lombó, S Ruiz-Díaz, A Gutiérrez-Adán… - Animals, 2021 - mdpi.com
Simple Summary Proton nuclear magnetic resonance spectroscopy (1 H-NMR) is of special
interest for the analysis of metabolites present in seminal plasma and spermatozoa. This …

Decay of skin-specific gene modules in pangolins

B Pinto, R Valente, F Caramelo, R Ruivo… - Journal of Molecular …, 2023 - Springer
The mammalian skin exhibits a rich spectrum of evolutionary adaptations. The
pilosebaceous unit, composed of the hair shaft, follicle, and the sebaceous gland, is the …

Alterations of pleiotropic neuropeptide-receptor gene couples in Cetacea

R Valente, M Cordeiro, B Pinto, A Machado, F Alves… - BMC biology, 2024 - Springer
Background Habitat transitions have considerable consequences in organism homeostasis,
as they require the adjustment of several concurrent physiological compartments to maintain …

IKBA phosphorylation governs human sperm motility through ACC-mediated fatty acid beta-oxidation

Y Li, Y Hu, Z Wang, T Lu, Y Yang, H Diao… - Communications …, 2023 - nature.com
The nuclear factor-κB (NF-κB) signaling pathway regulates specific immunological
responses and controls a wide range of physiological processes. NF-κB inhibitor alpha …

Glucose prevents the acquisition of the capacitated state in pig spermatozoa

R Serrano, S Solar Málaga, L González‐Fernández… - …, 2024 - Wiley Online Library
Background Mammalian spermatozoa need to undergo a process named capacitation to be
able to fertilize an oocyte. During their journey in the female tract, spermatozoa obtain …

Drosophila melanogaster sperm turn more oxidative in the female

C Wetzker, C Froschauer, C Massino… - Journal of …, 2024 - journals.biologists.com
Males and females of many species store sperm for extended periods. During storage,
sperm are predicted to undergo cellular and functional changes, especially towards …

Functional or vestigial? The genomics of the pineal gland in Xenarthra

R Valente, F Alves, I Sousa-Pinto, R Ruivo… - Journal of Molecular …, 2021 - Springer
Vestigial organs are historical echoes of past phenotypes. Determining whether a specific
organ constitutes a functional or vestigial structure can be a challenging task, given that …

Convergent Decay of Skin-specific Gene Modules in Pangolins

B Pinto, R Valente, F Caramelo, R Ruivo, LFC Castro - bioRxiv, 2022 - biorxiv.org
The Mammalia skin exhibits a rich spectrum of evolutionary adaptations. The pilosebaceous
unit, composed of the hair shaft, follicle, and the sebaceous gland, is the most striking …

Metabolism: Evolution of dolphin sperm endurance

LN Cooper - Current Biology, 2021 - cell.com
Mammalian sperm have long been known to use energy derived from the metabolism of
sugars and fatty acids. A new study shows that sperm of dolphins and their relatives lost …