Using genetic variation to predict and extend long-term kidney transplant function

MJ Simmonds - Transplantation, 2015 - journals.lww.com
Renal transplantation has transformed the life of patients with end-stage renal disease and
other chronic kidney disorders by returning endogenous kidney function and enabling …

[HTML][HTML] Genetic variation at the microRNA binding site of CAV1 gene is associated with lung cancer susceptibility

X Fang, X Li, Z Yin, L Xia, X Quan, Y Zhao, B Zhou - Oncotarget, 2017 - ncbi.nlm.nih.gov
Single nucleotide polymorphism (SNP) may influence the genesis and development of
cancer in a variety of ways depending on their location. Here we conducted a study in …

Genetic predictors of long-term graft function in kidney and pancreas transplant patients

CE Duff, MJ Simmonds - Briefings in functional genomics, 2017 - academic.oup.com
Kidney and pancreas transplantation have helped transform the lives of people with end-
stage renal failure and individuals with type 1 diabetes who have poor glycaemic …

Gene therapy in kidney transplantation: evidence of efficacy and future directions

J Li, G Qi, G Tu, C Yang, R Rong - Current Gene Therapy, 2017 - ingentaconnect.com
Allograft loss remains a severe clinical problem after kidney transplantation. The molecular
mechanism of graft loss is a complex process involving T and/or B cell activation …

Caveolin-1 rs4730751 single-nucleotide polymorphism may not influence kidney transplant allograft survival

M Maanaoui, R Lenain, A Hamroun… - Scientific Reports, 2019 - nature.com
Caveolin-1 is a protein (encoded by the CAV1 gene) supposedly harboring a protective
effect against fibrosis. CAV1 rs4730751 single nucleotide polymorphism (SNP) AA genotype …

Caveolin-1 rs4730751 gene polymorphism in kidney allograft recipients

S Słuczanowska-Głąbowska, D Malinowski… - Journal of Applied …, 2018 - Elsevier
Caveolin-1 is a phosphoprotein that plays a crucial role in tissue remodeling and fibrotic
pathways, controlling fibroblast function, proliferation, and apoptosis. Here we aimed to …

Different effects of CAV1 rs3807990 veriation on lipid profile in patiens with coronary heart disease based ob presence of diabetes

Ö Kurnaz-Gömleksiz, S İlikay, Z Buğra, O Öztürk… - 2020 - openaccess.altinbas.edu.tr
Amaç: Vasküler endotelyumun antiaterojenik fonksiyonunun azalması endotel disfonksiyona
sebep olmaktadır. Aterosklerotik sürecin gelişiminde önemli bir mekanizma olan endotel …

[PDF][PDF] KORONER KALP HASTALARINDA CAV1 rs3807990 VARYASYONUNUN LİPİD PROFİLİNDE DİYABETİK KOŞULLARA GÖRE FARKLI ETKİLERİ

Ö Kurnaz-GömleksIz, S IlIkay, Z Buğra… - İstanbul Tıp Fakültesi …, 2020 - dergipark.org.tr
Amaç: Vasküler endotelyumun antiaterojenik fonksiyonunun azalması endotel disfonksiyona
sebep olmaktadır. Aterosklerotik sürecin gelişiminde önemli bir mekanizma olan endotel …

[PDF][PDF] Bedeutung von genetischen Polymorphismen im MTOR-Gen bei Patienten nach Nierentransplantation unter und ohne mTOR-Inhibitor-Therapie

AK Nierhoff - 2019 - duepublico2.uni-due.de
1. Teile dieser Doktorarbeit wurden bzw. werden gerade publiziert: Nierhoff, A.*, Krull, M.*,
Hoerning, A., Wilde, B., Gäckler, A., Rohn, H., Witzke, O., Hagemann, A., Bachmann, HS …

[PDF][PDF] Utilizing genetic variation to predict and extend long-term kidney transplant function

MJ Simmonds - 2015 - core.ac.uk
ABCB1= ATP-binding cassette sub-family B member 1 APOL1= Apolipoprotein L1 AUC=
Area Under the Curve BMI= Body Mass Index Cav-1= caveolin-1 Cav-2= caveolin-2 Cnb1 …