Beta-globin gene haplotypes among cameroonians and review of the global distribution: is there a case for a single sickle mutation origin in Africa?
VJN Bitoungui, GD Pule, N Hanchard… - Omics: a journal of …, 2015 - liebertpub.com
Studies of hemoglobin S haplotypes in African subpopulations have potential implications
for patient care and our understanding of genetic factors that have shaped the prevalence of …
for patient care and our understanding of genetic factors that have shaped the prevalence of …
[HTML][HTML] Fatal sickle cell disease and Zika virus infection in girl from Colombia
L Arzuza-Ortega, A Polo, G Pérez-Tatis… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
Fatal Sickle Cell Disease and Zika Virus Infection in Girl from Colombia further tested with
Zika virus–specific real-time quantitative RT-PCR (2) by using the QuantiTect Probe RT-PCR …
Zika virus–specific real-time quantitative RT-PCR (2) by using the QuantiTect Probe RT-PCR …
Newborn screening for sickle cell disease in the Caribbean: an update of the present situation and of the disease prevalence
J Knight-Madden, K Lee, G Elana, N Elenga… - International journal of …, 2019 - mdpi.com
The region surrounding the Caribbean Sea is predominantly composed of island nations for
its Eastern part and the American continental coast on its Western part. A large proportion of …
its Eastern part and the American continental coast on its Western part. A large proportion of …
The effects of old and recent migration waves in the distribution of HBB* S globin gene haplotypes
JD Lindenau, SC Wagner, SM Castro… - Genetics and molecular …, 2016 - SciELO Brasil
Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta
(β) globin chain. The HBB* S gene is in linkage disequilibrium with five main haplotypes in …
(β) globin chain. The HBB* S gene is in linkage disequilibrium with five main haplotypes in …
Hydroxyurea alters hematological, biochemical and inflammatory biomarkers in Brazilian children with SCA: Investigating associations with βS haplotype and α …
SCMA Yahouédéhou, CC da Guarda, CVB Figueiredo… - PloS one, 2019 - journals.plos.org
This study investigated the effects of hydroxyurea (HU) on hematological, biochemical and
inflammatory parameters in children with sickle cell anemia (SCA) in association with βS …
inflammatory parameters in children with sickle cell anemia (SCA) in association with βS …
[HTML][HTML] Genetic variants associated with fetal hemoglobin levels show the diverse ethnic origin in Colombian patients with sickle cell anemia
Introduction: Fetal hemoglobin is an important factor in modulating the severity of sickle cell
anemia. Its level in peripheral blood underlies strong genetic determination. Associated loci …
anemia. Its level in peripheral blood underlies strong genetic determination. Associated loci …
Integrating datasets on public health and clinical aspects of sickle cell disease for effective community-based research and practice
RD Isokpehi, CP Johnson, AN Tucker, A Gautam… - Diseases, 2020 - mdpi.com
Sickle cell disease (SCD) is a genetic disease that has multiple aspects including public
health and clinical aspects. The goals of the research study were to (1) understand the …
health and clinical aspects. The goals of the research study were to (1) understand the …
[PDF][PDF] HBB gene cluster haplotype diversity in sickle cell anemia patients of Chhattisgarh, India
B Lakkakula, S Pattnaik - J Appl Biol Biotechnol, 2021 - academia.edu
Sickle cell anemia (SCA) is one of the hereditary hemoglobin disorders in Indian
populations. An exceptionally high prevalence of SCA is observed in the populations of …
populations. An exceptionally high prevalence of SCA is observed in the populations of …
Molecular characterisation of sickle cell disease and classification of major haplotypes associated with the β-globin cluster (HBB gene) by means of SNP marker …
M Díaz-Matallana, I Briceño… - Annals of Human …, 2024 - Taylor & Francis
Background Colombia has a mestizo population and the prevalence of haemoglobin
variants varies according to each region, but heterozygous carriers can be found in all of …
variants varies according to each region, but heterozygous carriers can be found in all of …
Congolese children with sickle cell trait may exhibit glomerular hyperfiltration: a case control study
MN Aloni, RM Ngiyulu, CN Nsibu… - Journal of Clinical …, 2017 - Wiley Online Library
Background The prevalence of sickle cell trait is extremely high in sub‐Saharan Africa.
Recent studies have reported the impact of sickle cell carriers on renal function. However …
Recent studies have reported the impact of sickle cell carriers on renal function. However …