Until recently, the intrinsically high level of cross-talk between immune cells, the complexity
of immune cell development, and the pleiotropic nature of cytokine signaling have …

Coordinated function of the innate and adaptive arms of the immune system in vertebrates is
essential to promote protective immunity and to avoid immunopathology. The Notch …

Siloed or singular system approach to disease management is common practice,
developing out of traditional medical school education. Textbooks of medicine describe a …

Increasing incidences of obesity and diabetes have made diabetic kidney disease (DKD) the
leading cause of chronic kidney disease and end-stage renal disease worldwide. Despite …

Regulatory T cells (Tregs) constitute an attractive therapeutic target given their essential role
in controlling autoimmunity. However, recent animal studies provide evidence for functional …

Abstract Background/Aims: Mindfulness-based stress reduction (MBSR) has enhanced
cognition, positive emotion, and immunity in younger and middle-aged samples; its benefits …

The remarkable plasticity of CD4+ T cells allows individuals to respond to environmental
stimuli in a context‐dependent manner. A balance of CD4+ T cell subsets is critical to mount …

The mucosal immune system defends against a vast array of pathogens, yet it exhibits
limited responses to commensal microorganisms under healthy conditions. The oral …

Breastfeeding is a gold standard of neonate nutrition because human milk contains a lot of
essential compounds crucial for proper development of a child. However, milk is also a …

Allergic asthma is a chronic airway inflammatory disease in which exposure to allergens
causes intermittent attacks of breathlessness, airway hyper-reactivity, wheezing, and …