[HTML][HTML] Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections

AH de Nooijer, P Pickkers, MG Netea, M Kox - Journal of Critical Care, 2023 - Elsevier
Mortality in acute infections is mostly associated with sepsis, defined as 'life-threatening
organ dysfunction caused by a dysregulated host response to infection'. It remains …

Insights into molecular structure of pterins suitable for biomedical applications

AA Buglak, MA Kapitonova, YL Vechtomova… - International Journal of …, 2022 - mdpi.com
Pterins are an inseparable part of living organisms. Pterins participate in metabolic reactions
mostly as tetrahydropterins. Dihydropterins are usually intermediates of these reactions …

Deep immunophenotyping reveals biomarkers of multisystemic inflammatory syndrome in children in a Latin American cohort

E Rey-Jurado, Y Espinosa, C Astudillo… - Journal of Allergy and …, 2022 - Elsevier
Background Multisystemic inflammatory syndrome in children (MIS-C) is a life-threatening
disease that occurs 2-5 weeks after severe acute respiratory syndrome coronavirus 2 …

Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression

CM Zobel, W Wenzel, JP Krüger… - Frontiers in …, 2023 - frontiersin.org
Background COVID-19 can show a variable course, from asymptomatic infections to acute
respiratory failure and death. For efficient allocation of resources, patients should be …

Clues to Disease Activity in Juvenile Dermatomyositis: neopterin and other biomarkers

A Khojah, G Morgan, LM Pachman - Diagnostics, 2021 - mdpi.com
Easily accessible biomarkers are urgently needed to evaluate immune activation in Juvenile
Dermatomyositis (JDM). The goal of this retrospective study is to define immunological and …

Corona and reproduction, or why the corona vaccination does not result in infertility

AS Braun, K Feil, E Reiser, G Weiss… - Geburtshilfe und …, 2022 - thieme-connect.com
Hintergrund Mit Fortschreiten der COVID-19-Pandemie und der Entwicklung neuer
Impfstoffe wächst in der Öffentlichkeit die Sorge, dass sowohl eine Infektion mit dem SARS …

SERS Signature of SARS-CoV-2 in Saliva and Nasopharyngeal Swabs: Towards Perspective COVID-19 Point-of-Care Diagnostics

SM Berus, AB Nowicka, J Wieruszewska… - International Journal of …, 2023 - mdpi.com
In this study, the intrinsic surface-enhanced Raman spectroscopy (SERS)-based approach
coupled with chemometric analysis was adopted to establish the biochemical fingerprint of …

[HTML][HTML] Neopterin mediates sleep deprivation-induced microglial activation resulting in neuronal damage by affecting YY1/HDAC1/TOP1/IL-6 signaling

X Li, Z Kong, K Cai, F Qi, S Zhu - Journal of Advanced Research, 2024 - Elsevier
Introduction Sleep deprivation (SD) is a common disorder in modern society. Hippocampus
is an important region of the brain for learning, memory, and emotions. Dysfunction of …

[PDF][PDF] The novel biomarker, neopterin, can predict the severity of COVID-19.

C KARACAER, S YAYLACI, K ISSEVER… - European Review for …, 2022 - europeanreview.org
OBJECTIVE: SARS-CoV-2 infection primarily affects T-lymphocytes, particularly CD4+ and
CD8+ T cells. However, there is a need for simpler and less expensive laboratory tests with …

Macrophage Activation Syndrome in Coinciding Pandemics of Obesity and COVID-19: Worse than Bad

AB Engin, ED Engin, A Engin - Obesity and Lipotoxicity, 2024 - Springer
Epigenetic changes have long-lasting impacts, which influence the epigenome and are
maintained during cell division. Thus, human genome changes have required a very long …