Preventing microbial infections with natural phenolic compounds

K Ecevit, AA Barros, JM Silva, RL Reis - Future Pharmacology, 2022 - mdpi.com
The struggle between humans and pathogens has taken and is continuing to take countless
lives every year. As the misusage of conventional antibiotics increases, the complexity …

Naphthalene, a versatile platform in medicinal chemistry: sky-high perspective

S Makar, T Saha, SK Singh - European journal of medicinal chemistry, 2019 - Elsevier
Naphthalene, a cytotoxic moiety, is an extensively explored aromatic conjugated system with
applications in various pathophysiological conditions viz. anticancer, antimicrobial, anti …

Natural product growth inhibitors of Mycobacterium tuberculosis

BR Copp, AN Pearce - Natural Product Reports, 2007 - pubs.rsc.org
Covering: 2003–2005. Previous review: Nat. Prod. Rep., 2003, 20, 535–557 This review
covers natural products (secondary metabolites) with reported growth inhibitory activity …

Antituberculosis drug research: a critical overview

Beena, DS Rawat - Medicinal research reviews, 2013 - Wiley Online Library
The increasing drug resistance of M ycobacterium tuberculosis to the currently used drugs
and HIV coinfection has caused alarm in the international scientific community …

Synthesis, antibacterial and antifungal activities of naphthoquinone derivatives: a structure–activity relationship study

JM Sánchez-Calvo, GR Barbero… - Medicinal Chemistry …, 2016 - Springer
Abstract The synthesis of 1, 4-naphthoquinone derivatives is of great interest since these
compounds exhibit strong activity as antimalarial, antibacterial, antifungal and anticancer …

Antitubercular and antibacterial activity of quinonoid natural products against multi‐drug resistant clinical isolates

D Dey, R Ray, B Hazra - Phytotherapy research, 2014 - Wiley Online Library
Multi‐drug resistant Mycobacterium tuberculosis and other bacterial pathogens represent a
major threat to human health. In view of the critical need to augment the current drug regime …

Synthesis and biological evaluation of novel (L)-α-amino acid methyl ester, heteroalkyl, and aryl substituted 1, 4-naphthoquinone derivatives as antifungal and …

VK Tandon, DB Yadav, RV Singh… - Bioorganic & Medicinal …, 2005 - Elsevier
A series of (S)-N-(1, 4-naphthoquinon-2-yl)-α-amino acid methyl esters 3–9, 2-N, N-
dialkylamino-1, 4-naphthoquinones 10–11 and 2-hydroxy-3-(2′-mercaptoimidazolyl)-1, 4 …

Anti-infective quinone derivatives of recent patents

J Koyama - Recent Patents on Anti-Infective Drug Discovery, 2006 - benthamdirect.com
Quinones are important naturally occurring pigments widely distributed in nature and are
well known to demonstrate various physiological activities as antimicrobial and anticancer …

1,4-Benzoquinone antimicrobial agents against Staphylococcus aureus and Mycobacterium tuberculosis derived from scorpion venom

EN Carcamo-Noriega… - Proceedings of the …, 2019 - National Acad Sciences
Two 1, 4-benzoquinone derivatives, found in the venom of the scorpion Diplocentrus melici
following exposure to air, have been isolated, characterized, synthesized, and assessed for …

[HTML][HTML] Anti-biofilm performance of three natural products against initial bacterial attachment

M Salta, JA Wharton, SP Dennington… - International journal of …, 2013 - mdpi.com
Marine bacteria contribute significantly towards the fouling consortium, both directly (modern
foul release coatings fail to prevent “slime” attachment) and indirectly (biofilms often excrete …