Sixty-five years of the long march in protein secondary structure prediction: the final stretch?

Y Yang, J Gao, J Wang, R Heffernan… - Briefings in …, 2018 - academic.oup.com
Protein secondary structure prediction began in 1951 when Pauling and Corey predicted
helical and sheet conformations for protein polypeptide backbone even before the first …

Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering

L He, P Tan, L Zhu, K Huang, NT Nguyen… - Nature Chemical …, 2021 - nature.com
Plant-based photosensors, such as the light-oxygen-voltage sensing domain 2 (LOV2) from
oat phototropin 1, can be modularly wired into cell signaling networks to remotely control …

NMR-STAR: comprehensive ontology for representing, archiving and exchanging data from nuclear magnetic resonance spectroscopic experiments

EL Ulrich, K Baskaran, H Dashti, YE Ioannidis… - Journal of biomolecular …, 2019 - Springer
The growth of the biological nuclear magnetic resonance (NMR) field and the development
of new experimental technology have mandated the revision and enlargement of the NMR …

The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome

EA Morrison, S Bowerman, KL Sylvers… - Elife, 2018 - elifesciences.org
Histone tails harbor a plethora of post-translational modifications that direct the function of
chromatin regulators, which recognize them through effector domains. Effector …

Unraveling the meaning of chemical shifts in protein NMR

MV Berjanskii, DS Wishart - Biochimica et Biophysica Acta (BBA)-Proteins …, 2017 - Elsevier
Chemical shifts are among the most informative parameters in protein NMR. They provide
wealth of information about protein secondary and tertiary structure, protein flexibility, and …

Catalytic peptide-based coacervates for enhanced function through structural organization and substrate specificity

DQP Reis, S Pereira, AP Ramos, PM Pereira… - Nature …, 2024 - nature.com
Liquid-liquid phase separation (LLPS) in living cells provides innovative pathways for
synthetic compartmentalized catalytic systems. While LLPS has been explored for …

ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication

D Wang, J Ma, MV Botuyan, G Cui, Y Yan, D Ding… - Science …, 2021 - science.org
53BP1 activates nonhomologous end joining (NHEJ) and inhibits homologous
recombination (HR) repair of DNA double-strand breaks (DSBs). Dissociation of 53BP1 from …

Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation

C Zhang, C Guo, RW Russell, CM Quinn, M Li… - Nature …, 2022 - nature.com
Microtubules (MTs) and their associated proteins play essential roles in maintaining cell
structure, organelle transport, cell motility, and cell division. Two motors, kinesin and …

The human CRY1 tail controls circadian timing by regulating its association with CLOCK: BMAL1

GCG Parico, I Perez, JL Fribourgh… - Proceedings of the …, 2020 - National Acad Sciences
Circadian rhythms are generated by interlocked transcription–translation feedback loops
that establish cell-autonomous biological timing of∼ 24 h. Mutations in core clock genes that …

BioMagResBank (BMRB) as a resource for structural biology

PR Romero, N Kobayashi, JR Wedell… - … : Methods and Protocols, 2020 - Springer
Abstract The Biological Magnetic Resonance Data Bank (BioMagResBank or BMRB),
founded in 1988, serves as the archive for data generated by nuclear magnetic resonance …