Executable biochemical space for specification and analysis of biochemical systems

M Troják, D Šafránek, L Brim, J Šalagovič… - Electronic Notes in …, 2020 - Elsevier
We present the second generation of a rule-based language called Biochemical Space
Language (BCSL) that combines the advantages of different approaches and thus makes an …

Regulated multiset rewriting systems

M Troják, S Pastva, D Šafránek, L Brim - arXiv preprint arXiv:2111.13036, 2021 - arxiv.org
Multiset rewriting systems provide a formalism particularly suitable for the description of
biological systems. We present an extension of this formalism with additional controls on the …

Accessible Pattern Analyses in Kappa Models

J FERET - Symbolic Approaches to Modeling and Analysis of …, 2023 - books.google.com
Describing and analyzing the large-scale and highly combinatorial systems that arise from
certain mechanistic models in systems biology is still beyond the reach of recent …

eBCSgen: a software tool for biochemical space language

M Troják, D Šafránek, L Mertová, L Brim - Computational Methods in …, 2020 - Springer
Abstract eBCSgen is a tool for development and analysis of models written in Biochemical
Space Language (BCSL). BCSL is a rule-based language for biological systems designed …

TRuML: a translator for rule-based modeling languages

R Suderman, WS Hlavacek - Proceedings of the 8th ACM International …, 2017 - dl.acm.org
Rule-based modeling languages, such as the Kappa and BioNetGen languages (BNGL),
are powerful frameworks for modeling the dynamics of complex biochemical reaction …

Analyse statique et réduction de modèles pour un langage de réécriture de graphes à sites

J Feret - 2023 - inria.hal.science
Les sciences du logiciel ont un rôle à jouer pour décrire, organiser, exécuter et analyser les
systèmes d'interactions moléculaires tels que les voies de signalisation biologiques. Ceux-ci …

Modélisation en langage Kappa de la dynamique des cellules étoilées hépatiques durant le développement et la réversion de la fibrose

M Bouguéon - 2023 - inria.hal.science
La fibrose hépatique est une réponse de cicatrisation excessive induite par des lésions
chroniques. Elle se caractérise par une accumulation de matrice extracellulaire (MEC) …

Continuous-time temporal logic specification and verification for nonlinear biological systems in uncertain contexts

T Wright - 2022 - era.ed.ac.uk
In this thesis we introduce a complete framework for modelling and verification of biological
systems in uncertain contexts based on the bond-calculus process algebra and the LBUC …

[PDF][PDF] Multi-Scale Modeling and Simulation of Cell Signaling and Transport in Renal Collecting Duct Principal Cells

C Leberecht - 2022 - core.ac.uk
The response of cells to their environment is driven by a variety of proteins and messenger
molecules. In eukaryotes, their distribution and location in the cell is regulated by the …

Analyses des motifs accessibles dans les modèles Kappa

J Feret - 2020 - books.google.com
Décrire et analyser les systèmes à grande échelle et fortement combinatoires qui sont issus
de certains modèles mécanistiques de biologie des systèmes est encore hors de portée de …