REASSURED multiplex diagnostics: a critical review and forecast

JA Otoo, TS Schlappi - Biosensors, 2022 - mdpi.com
The diagnosis of infectious diseases is ineffective when the diagnostic test does not meet
one or more of the necessary standards of affordability, accessibility, and accuracy. The …

Recent advances on CRISPR/Cas system-enabled portable detection devices for on-site agri-food safety assay

M Qiu, J Zhang, L Pang, Y Zhang, Q Zhao… - Trends in Food Science …, 2022 - Elsevier
Background Agri-food safety has been considered as one of the most important public
concerns worldwide. From farm to table, food crops and foods are extremely vulnerable to …

Diagnostic assay and technology advancement for detecting SARS-CoV-2 infections causing the COVID-19 pandemic

BC Dhar - Analytical and Bioanalytical Chemistry, 2022 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-caused COVID-19
pandemic has transmitted to humans in practically all parts of the world, producing socio …

Mechanistic insights of CRISPR/Cas nucleases for programmable targeting and early-stage diagnosis: A review

J de Dieu Habimana, R Huang, B Muhoza… - Biosensors and …, 2022 - Elsevier
Conventional and routine diagnostics such as polymerase chain reaction (PCR) and
serological tests are less sensitive, costly, and require sample pretreatment procedures …

Loop-mediated isothermal amplification-integrated CRISPR methods for infectious disease diagnosis at point of care

D Yigci, N Atçeken, AK Yetisen, S Tasoglu - ACS omega, 2023 - ACS Publications
Infectious diseases continue to pose an imminent threat to global public health, leading to
high numbers of deaths every year and disproportionately impacting developing countries …

Enzyme-assisted nucleic acid amplification in molecular diagnosis: a review

M Wang, H Liu, J Ren, Y Huang, Y Deng, Y Liu, Z Chen… - Biosensors, 2023 - mdpi.com
Infectious diseases and tumors have become the biggest medical challenges in the 21st
century. They are driven by multiple factors such as population growth, aging, climate …

CRISPR‐Based Programmable Nucleic Acid‐Binding Protein Technology Can Specifically Detect Fatal Tropical Disease‐Causing Pathogens

MR Rahman, TR Majumder, MAI Apu… - Journal of Tropical …, 2022 - Wiley Online Library
Diagnostic approaches capable of ultrasensitive pathogen detection from low‐volume
clinical samples, running without any sophisticated instrument and laboratory setup, are …

Dual-mode sensing of Mycobacterium tuberculosis with DNA-functionalized gold nanoparticles and asymmetric RPA-triggered PAM-free CRISPR system

L Zhang, H Bai, C Zhang, X He, J Zou, W Bai… - Sensors and Actuators B …, 2025 - Elsevier
Mycobacterium tuberculosis (MTB) causes the ancient infectious disease of tuberculosis,
and its rapid, specific, and sensitive detection has long been a challenging endeavor …

A Primer on Gene Editing: What Does It Mean for Pathologists?

A Cushman-Vokoun, RJ Schmidt… - … of pathology & …, 2024 - meridian.allenpress.com
Context Gene editing–based therapies are currently in development in the areas of
oncology, inherited disease, and infectious disease. These potentially life-altering therapies …

Strategies and challenges of CRISPR/Cas system in detecting foodborne pathogens

AAS Janudin, YC Lim, MU Ahmed - Biosensors for Foodborne Pathogens …, 2024 - Elsevier
Nucleic acid-based alternatives, including polymerase chain reaction, nucleic acid
hybridization, and isothermal amplification techniques, satisfy the requirement of rapid and …