[HTML][HTML] Ginsenosides in Panax genus and their biosynthesis

M Hou, R Wang, S Zhao, Z Wang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Ginsenosides are a series of glycosylated triterpenoids which belong to protopanaxadiol
(PPD)-, protopanaxatriol (PPT)-, ocotillol (OCT)-and oleanane (OA)-type saponins known as …

Biosynthesis and biotechnological production of ginsenosides

YJ Kim, D Zhang, DC Yang - Biotechnology advances, 2015 - Elsevier
Medicinal plants are essential for improving human health, and around 75% of the
population in developing countries relies mainly on herb-based medicines for health care …

[HTML][HTML] Synthesizing ginsenoside Rh2 in Saccharomyces cerevisiae cell factory at high-efficiency

P Wang, W Wei, W Ye, X Li, W Zhao, C Yang, C Li… - Cell discovery, 2019 - nature.com
Synthetic biology approach has been frequently applied to produce plant rare bioactive
compounds in microbial cell factories by fermentation. However, to reach an ideal …

Panax ginseng genome examination for ginsenoside biosynthesis

J Xu, Y Chu, B Liao, S Xiao, Q Yin, R Bai, H Su… - …, 2017 - academic.oup.com
Ginseng, which contains ginsenosides as bioactive compounds, has been regarded as an
important traditional medicine for several millennia. However, the genetic background of …

Triterpenoid-biosynthetic UDP-glycosyltransferases from plants

S Rahimi, J Kim, I Mijakovic, KH Jung, G Choi… - Biotechnology …, 2019 - Elsevier
Triterpenoid saponins are naturally occurring structurally diverse glycosides of triterpenes
that are widely distributed among plant species. Great interest has been expressed by …

[HTML][HTML] Engineering yeast for the production of plant terpenoids using synthetic biology approaches

JA Bureau, ME Oliva, Y Dong, C Ignea - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2011–2022 The low amounts of terpenoids produced in plants and the difficulty in
synthesizing these complex structures have stimulated the production of terpenoid …

Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance

T Biswas, UN Dwivedi - Protoplasma, 2019 - Springer
The saponins are a diverse class of natural products, with a broad scale distribution across
different plant species. Chemically characterized as triterpenoid glycosides, they posses a …

Advances in the biosynthesis and metabolic engineering of rare ginsenosides

M Li, M Ma, Z Wu, X Liang, Q Zheng, D Li, T An… - Applied Microbiology …, 2023 - Springer
Rare ginsenosides are the deglycosylated secondary metabolic derivatives of major
ginsenosides, and they are more readily absorbed into the bloodstream and function as …

Plant secondary metabolism linked glycosyltransferases: An update on expanding knowledge and scopes

P Tiwari, RS Sangwan, NS Sangwan - Biotechnology Advances, 2016 - Elsevier
The multigene family of enzymes known as glycosyltransferases or popularly known as GTs
catalyze the addition of carbohydrate moiety to a variety of synthetic as well as natural …

P450s and UGTs: key players in the structural diversity of triterpenoid saponins

H Seki, K Tamura, T Muranaka - Plant and Cell Physiology, 2015 - academic.oup.com
The recent spread of next-generation sequencing techniques has facilitated transcriptome
analyses of non-model plants. As a result, many of the genes encoding enzymes related to …