Making sense of strengths and weaknesses observed in adolescent laboratory rodents

WC Lin, L Wilbrecht - Current Opinion in Psychology, 2022 - Elsevier
During adolescence, rodents disperse from their natal site, find a new home, and navigate
social relationships and threats. Although rats and mice in the laboratory cannot fully …

Quantifying the instrumental and noninstrumental underpinnings of Pavlovian responding with the Price equation

PS Strand, MJF Robinson, KR Fiedler, R Learn… - Psychonomic bulletin & …, 2021 - Springer
The Price equation is a mathematical expression of selectionist and non-selectionist
pressures on biological, cultural, and behavioral change. We use it here to specify …

Reward-mediated, model-free reinforcement-learning mechanisms in Pavlovian and instrumental tasks are related

NM Afshar, F Cinotti, D Martin, M Khamassi… - Journal of …, 2023 - Soc Neuroscience
Model-free and model-based computations are argued to distinctly update action values that
guide decision-making processes. It is not known, however, if these model-free and model …

Sign tracking predicts suboptimal behavior in a rodent gambling task

M Swintosky, JT Brennan, C Koziel, JP Paulus… - …, 2021 - Springer
Rationale Reward-associated cues can promote maladaptive behavior, including risky
decision-making in a gambling setting. A propensity for sign tracking over goal tracking—ie …

Basolateral amygdala to nucleus accumbens communication differentially mediates devaluation sensitivity of sign-and goal-tracking rats

DE Kochli, SE Keefer, U Gyawali… - Frontiers in Behavioral …, 2020 - frontiersin.org
Rats rely on communication between the basolateral amygdala (BLA) and nucleus
accumbens (NAc) to express lever directed approach in a Pavlovian lever autoshaping …

[HTML][HTML] Reward-predictive cues elicit excessive reward seeking in adolescent rats

AT Marshall, CN Munson, NT Maidment… - Developmental cognitive …, 2020 - Elsevier
Impulsive behavior during adolescence may stem from developmental imbalances between
motivational and cognitive-control systems, producing greater urges to pursue reward and …

Propensity for risky choices despite lower cue reactivity in adolescent rats

S Zeng, EFB McLaughlin, A Ramesh… - Frontiers in Behavioral …, 2023 - frontiersin.org
Adolescence is a time of heightened risk-taking across species. Salient audiovisual cues
associated with rewards are a common feature of gambling environments and have been …

Fractionating impulsivity and reward-related phenotypes in adolescent mice

R Albert-Lyons, SS Desrochers, C Fengler… - Behavioural Brain …, 2025 - Elsevier
Adolescence is a developmental period characterized by changes in the brain and behavior,
including heightened reward seeking, increased impulsivity, and elevated risk-taking …

Excitatory and Inhibitory Signaling in the Nucleus Accumbens Encode Different Aspects of a Pavlovian Cue in Sign Tracking and Goal Tracking Rats

K Duffer, ZS Gillis, SE Morrison - eneuro, 2023 - eneuro.org
When a Pavlovian cue is presented separately from its associated reward, some animals will
acquire a sign tracking (ST) response–approach and/or interaction with the cue–while …

Differential dopamine dynamics in adolescents and adults

B Toth - Journal of Neuroscience, 2022 - Soc Neuroscience
Why do adolescents have a high propensity to engage in maladaptive behaviors? One
explanation is that the adolescent nervous system is still undergoing maturation, and …