Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …
and influence cellular function via effects on membrane properties, and also by acting as a …
Understanding FAHFAs: From structure to metabolic regulation
K Brejchova, L Balas, V Paluchova, M Brezinova… - Progress in lipid …, 2020 - Elsevier
The discovery of branched fatty acid esters of hydroxy fatty acids (FAHFAs) in humans draw
attention of many researches to their biological effects. Although FAHFAs were originally …
attention of many researches to their biological effects. Although FAHFAs were originally …
Insulin action in adipocytes, adipose remodeling, and systemic effects
On this 100 th anniversary of the discovery of insulin, we recognize the critical role that
adipocytes, which are exquisitely responsive to insulin, have played in determining the …
adipocytes, which are exquisitely responsive to insulin, have played in determining the …
Branched and linear fatty acid esters of hydroxy fatty acids (FAHFA) relevant to human health
M Riecan, V Paluchova, M Lopes, K Brejchova… - Pharmacology & …, 2022 - Elsevier
Fatty acid esters of hydroxy fatty acids (FAHFAs) represent a complex lipid class that
contains both signaling mediators and structural components of lipid biofilms in humans …
contains both signaling mediators and structural components of lipid biofilms in humans …
Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs)
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are endogenous lipids with
antidiabetic and anti-inflammatory effects. Each FAHFA family consists of esters with …
antidiabetic and anti-inflammatory effects. Each FAHFA family consists of esters with …
Exploring foods as natural sources of FAHFAs—A review of occurrence, extraction, analytical techniques and emerging bioactive potential
TM Olajide, W Cao - Trends in Food Science & Technology, 2022 - Elsevier
Background Fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of recently
discovered novel lipids gaining increasing attention due to their diverse biological roles …
discovered novel lipids gaining increasing attention due to their diverse biological roles …
The role of peroxiredoxin 6 in biosynthesis of FAHFAs
V Paluchova, T Cajka, T Durand, C Vigor… - Free Radical Biology …, 2022 - Elsevier
Abstract Peroxiredoxin 6 (Prdx6) is a multifunctional enzyme, a unique member of the
peroxiredoxin family, with an important role in antioxidant defense. Moreover, it has also …
peroxiredoxin family, with an important role in antioxidant defense. Moreover, it has also …
Krill oil supplementation reduces exacerbated hepatic steatosis induced by thermoneutral housing in mice with diet-induced obesity
G Sistilli, V Kalendova, T Cajka, I Irodenko, K Bardova… - Nutrients, 2021 - mdpi.com
Preclinical evidence suggests that n-3 fatty acids EPA and DHA (Omega-3) supplemented
as phospholipids (PLs) may be more effective than triacylglycerols (TAGs) in reducing …
as phospholipids (PLs) may be more effective than triacylglycerols (TAGs) in reducing …
Metabolomics atlas of oral 13C-glucose tolerance test in mice
M Lopes, K Brejchova, M Riecan, M Novakova… - Cell Reports, 2021 - cell.com
Glucose tolerance represents a complex phenotype in which many tissues play important
roles and interact to regulate metabolic homeostasis. Here, we perform an analysis of 13 C 6 …
roles and interact to regulate metabolic homeostasis. Here, we perform an analysis of 13 C 6 …
Adipose tissue-derived lipokines in metabolism
Adipose tissue is a crucial regulator of metabolism with functions that include energy storage
and dissipation as well as the secretion of bioactive molecules. As the largest endocrine …
and dissipation as well as the secretion of bioactive molecules. As the largest endocrine …