Age-related mitochondrial dysfunction as a key factor in COVID-19 disease

DJM Fernández-Ayala, P Navas… - Experimental gerontology, 2020 - Elsevier
SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …

Mitochondria at work: new insights into regulation and dysregulation of cellular energy supply and metabolism

V Schirrmacher - Biomedicines, 2020 - mdpi.com
Mitochondria are of great relevance to health, and their dysregulation is associated with
major chronic diseases. Research on mitochondria—156 brand new publications from 2019 …

[HTML][HTML] A volatile from the skin microbiota of flavivirus-infected hosts promotes mosquito attractiveness

H Zhang, Y Zhu, Z Liu, Y Peng, W Peng, L Tong… - Cell, 2022 - cell.com
The host-seeking activity of hematophagous arthropods is essential for arboviral
transmission. Here, we demonstrate that mosquito-transmitted flaviviruses can manipulate …

[HTML][HTML] the pathogenesis of long-term neuropsychiatric COVID-19 and the role of microglia, mitochondria, and persistent neuroinflammation: a hypothesis

GB Stefano, P Büttiker, S Weissenberger… - … medical journal of …, 2021 - ncbi.nlm.nih.gov
Persistent comorbidities occur in patients who initially recover from acute coronavirus
disease 2019 (COVID-19) due to infection with severe acute respiratory syndrome …

Restructured membrane contacts rewire organelles for human cytomegalovirus infection

KC Cook, E Tsopurashvili, JM Needham… - Nature …, 2022 - nature.com
Membrane contact sites (MCSs) link organelles to coordinate cellular functions across space
and time. Although viruses remodel organelles for their replication cycles, MCSs remain …

Mitochondrial dysfunction and coenzyme Q10 supplementation in post-viral fatigue syndrome: an overview

D Mantle, IP Hargreaves, JC Domingo… - International Journal of …, 2024 - mdpi.com
Post-viral fatigue syndrome (PVFS) encompasses a wide range of complex neuroimmune
disorders of unknown causes characterised by disabling post-exertional fatigue, myalgia …

miRNAs, from evolutionary junk to possible prognostic markers and therapeutic targets in COVID-19

B Bautista-Becerril, G Pérez-Dimas… - Viruses, 2021 - mdpi.com
The COVID-19 pandemic has been a public health issue around the world in the last few
years. Currently, there is no specific antiviral treatment to fight the disease. Thus, it is …

Biomedical perspectives of acute and chronic neurological and neuropsychiatric sequelae of COVID-19

GB Stefano, P Büttiker, S Weissenberger… - Current …, 2022 - benthamdirect.com
The incidence of infections from severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), the etiologic agent for coronavirus disease 2019 (COVID-19), has dramatically …

Potential prion involvement in long COVID-19 neuropathology, including behavior

GB Stefano, P Büttiker, S Weissenberger… - Cellular and Molecular …, 2023 - Springer
Prion'is a term used to describe a protein infectious particle responsible for several
neurodegenerative diseases in mammals, eg, Creutzfeldt-Jakob disease. The novelty is that …

Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID

AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …