Recent advances in modified chitosan-based drug delivery systems for transmucosal applications: A comprehensive review

MHA Elella, OM Kolawole - International Journal of Biological …, 2024 - Elsevier
In recent years, transmucosal drug delivery systems (TDDSs) have been extensively studied
because they protect therapeutic agents from degradation; improve drug residence time at …

Microfluidic fabrication of encapsulated probiotic microspheres using cysteine-modified chitosan with dual functions of bacterial adhesion and intestinal mucosal …

Y Luo, Z Ma, C De Souza, S Wang, F Qiao, H Yi… - Food …, 2024 - Elsevier
Compared with previous encapsulation methods, the emerging microfluidic approach has
the potential of preparing monodispersed particles with considerable advantages, such as …

A Micro-In-Macro Gastroretentive System for the Delivery of Narrow-Absorption Window Drugs

M Govender, TA Rants'o, YE Choonara - Polymers, 2023 - mdpi.com
A micro-in-macro gastroretentive and gastrofloatable drug delivery system (MGDDS), loaded
with the model-drug ciprofloxacin, was developed in this study to address the limitations …

Tailoring the properties of chitosan by grafting with 2-mercaptobenzoic acid to improve mucoadhesion: in silico studies, synthesis and characterization

TK Marwaha, A Madgulkar, M Bhalekar… - Progress in …, 2022 - Springer
Mucoadhesive polymers improve oral bioavailability of drugs by prolonging the duration of
adhesion of drugs with mucosa. Various methods could be employed to address the …

[PDF][PDF] Development of a Eudragit-Chitosan Nanosystem for the pH-Dependent Transport of Duloxetine to the Brain: Synthesis, Characterization and In Silico Modeling …

PPD Kondiah, S Mdanda, SS Makhathini… - …, 2022 - academia.edu
The purpose of this study was to synthesize duloxetine (DLX)-loaded Eudragit-Chitosan
(Eud-CHT) nanoparticles enclosed in an oral gelatin capsule and to evaluate the potential to …

Design, Optimization, and Evaluation of Chitosan-2-mercaptobenzoic Acid as a Dual-functionalized Thiomer

TK Marwaha, A Madgulkar… - Current Applied Polymer …, 2024 - benthamdirect.com
Aims This study aimed to develop and evaluate mucoadhesive microspheres for the
controlled release of zidovudine using a novel dual-functionalized polymer. Background …

Spectroscopic cyclic voltammetry, and molecular docking study on the molecular interaction between synthesized blue emitting nitrogen‐doped carbon dots and …

Y Liu, L Zhang, YH Liang, H Yang, X Guo… - Nano Select, 2022 - Wiley Online Library
Fluorescent carbon dots are a promising drug carrier and bio‐sensor material. The study
between human serum albumin and carbon dots could explore the possible interaction …

[PDF][PDF] A Micro-In-Macro Gastroretentive System for the Delivery of Narrow-Absorption Window Drugs. Polymers 2023, 15, 1385

M Govender, TA Rants'o, YE Choonara - 2023 - researchgate.net
A micro-in-macro gastroretentive and gastrofloatable drug delivery system (MGDDS), loaded
with the model-drug ciprofloxacin, was developed in this study to address the limitations …