Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders

A Markov, L Thangavelu, S Aravindhan… - Stem cell research & …, 2021 - Springer
Over recent years, mesenchymal stem/stromal cells (MSCs) and their potential biomedical
applications have received much attention from the global scientific community in an …

Transforming growth factor-β in tumour development

CB Trelford, L Dagnino… - Frontiers in Molecular …, 2022 - frontiersin.org
Transforming growth factor-β (TGFβ) is a ubiquitous cytokine essential for embryonic
development and postnatal tissue homeostasis. TGFβ signalling regulates several biological …

Efficacy and Safety of Mesenchymal Stem Cell Transplantation in the Treatment of Autoimmune Diseases (Rheumatoid Arthritis, Systemic Lupus Erythematosus …

L Zeng, G Yu, K Yang, W Xiang, J Li… - Stem cells …, 2022 - Wiley Online Library
Objective. To evaluate the efficacy and safety of mesenchymal stem cell (MSC)
transplantation in the treatment of autoimmune diseases. Methods. The Chinese and …

Tissue regeneration: the crosstalk between mesenchymal stem cells and immune response

K Qi, N Li, Z Zhang, G Melino - Cellular immunology, 2018 - Elsevier
Mesenchymal stem cells (MSCs) exist in almost all tissues with the capability to differentiate
into several different cell types and hold great promise in tissue repairs in a cell replacement …

Concise review: fat and furious: harnessing the full potential of adipose-derived stromal vascular fraction

JA Dykstra, T Facile, RJ Patrick… - Stem cells …, 2017 - academic.oup.com
Due to their capacity to self-renew, proliferate and generate multi-lineage cells, adult-
derived stem cells offer great potential for use in regenerative therapies to stop and/or …

Immunomodulatory characteristics of mesenchymal stem cells and their role in the treatment of multiple sclerosis

T Gharibi, M Ahmadi, N Seyfizadeh, F Jadidi-Niaragh… - Cellular …, 2015 - Elsevier
Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of central
nervous system (CNS). Although the main cause of MS is not clear, studies suggest that MS …

Stem cell technology for bone regeneration: current status and potential applications

G Asatrian, D Pham, WR Hardy… - Stem cells and cloning …, 2015 - Taylor & Francis
Continued improvements in the understanding and application of mesenchymal stem cells
(MSC) have revolutionized tissue engineering. This is particularly true within the field of …

The multifunction role of tumor-associated mesenchymal stem cells and their interaction with immune cells in breast cancer

A Chauhan, S Agarwal, M Masih… - Immunological …, 2023 - Taylor & Francis
Mesenchymal stem cells (MSCs) are a heterogeneous group of progenitor cells that play a
multifunctional role including tissue regeneration, self-renewal properties, and differentiate …

Current understanding of adipose-derived mesenchymal stem cell-based therapies in liver diseases

C Hu, L Zhao, L Li - Stem cell research & therapy, 2019 - Springer
The liver, the largest organ with multiple synthetic and secretory functions in mammals,
consists of hepatocytes, cholangiocytes, hepatic stellate cells (HSCs), sinusoidal endothelial …

Mesenchymal stromal/stem cells as potential therapy in diabetic retinopathy

A Fiori, V Terlizzi, H Kremer, J Gebauer, HP Hammes… - Immunobiology, 2018 - Elsevier
Diabetic retinopathy (DR) is a multifactorial microvascular disease induced by
hyperglycemia and subsequent metabolic abnormalities. The resulting cell stress causes a …