Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

Chronic low-grade elevations of blood-borne cytokines/chemokines in older age tend to
associate with frailty in humans. This persistent inflammation is often called “inflammageing” …

A global pandemic has erupted as a result of the new brand coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …

Idiopathic inflammatory myopathies (IIM), even though sharing common clinical
manifestations, are characterized by diversified molecular pathogenetic mechanisms which …

Still's disease is a rare inflammatory syndrome that encompasses systemic juvenile
idiopathic arthritis and adult-onset Still's disease, both of which can exhibit life-threatening …

Background and aim Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disease
that is common in elderly people. Its classification in the spectrum of autoinflammatory and …

The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is an
essential component of the human innate immune system, and is closely associated with …

Activation of nicotinic acetylcholine receptors (nAChRs) expressed by innate immune cells
can attenuate pro-inflammatory responses. Silent nAChR agonists, which down-modulate …

IL-1, plays a role in some pathological inflammatory conditions. This pro-inflammatory
cytokine also has a crucial role in tumorigenesis and immune responses in the tumor …

The current SARS-CoV-2 pandemic diffused worldwide has encouraged the rapid
development of vaccines to counter the spread of the virus. At present in Italy, 75.01% of the …