After the publication of the revised edition, therapeutic drugs described in “Future Treatment”
were approved and important evidence for pharmacologic therapy and nonpharmacologic …

Acute coronary syndromes (ACS) are a comprehensive disease concept characterized by
acute myocardial ischemia caused by disruption of coronary artery plaque and consequent …

Heart Failure Society (JHFS). The working committee for this project includes members and
collaborators involved in the previous versions of the heart failure guidelines and members …

Background The new category of heart failure (HF), HF with mid‐range left ventricular
ejection fraction (LVEF)(HFmrEF), has recently been proposed. However, the clinical …

Little is known about specific modes of death in patients with heart failure with preserved
ejection fraction (HFpEF). Herein, the authors critically appraise the current state of data and …

OBJECTIVE Several studies have explored the impact of diabetes on mortality in patients
with heart failure (HF). However, the extent to which diabetes may confer risk of mortality and …

Japan has the highest proportion of older people in the world, 25.9% of the population were
aged 65 or above in 2014. Although there have been no population‐based studies that …

Heart failure (HF) is a major global healthcare problem with an estimated prevalence of
approximately 26 million. In Asia-Pacific regions, HF is associated with a significant …

Risk models, informing optimal long-term medical management, seldom use natriuretic
peptides (NP) in ascertaining the absolute risk of outcomes for HF patients. Individual …

Background Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the urinary albumin-
to-creatinine ratio (UACR) in patients with elevated levels of albuminuria in the presence or …