Sarcopenia prevalence and its clinical impact are reportedly variable in chronic obstructive
pulmonary disease (COPD) due partly to definition criteria. This review aimed to identify the …

Sarcopenia and frailty are geriatric syndromes characterized by multisystem decline, which
are related to and reflected by markers of skeletal muscle dysfunction. In older people …

Background Frailty is an important clinical syndrome that is consistently associated with
adverse outcomes in older people. The relevance of frailty to chronic respiratory disease …

Background The EQ-5D, a generic health status questionnaire that is widely used in health
economic evaluation, was recently expanded to the EQ-5D-5L to address criticisms of …

Importance The potential benefit of novel skeletal muscle anabolic agents to improve
physical function in people with sarcopenia and other muscle wasting diseases is unknown …

Background Muscle wasting and chronic inflammation are predominant features of patients
with COPD. Systemic inflammation is associated with an accelerated decline in lung …

The role of skeletal muscle mass in modulating immune response and supporting metabolic
stress has been increasingly confirmed. Patients with sarcopenia, characterized by reduced …

Background To describe the prevalence of sarcopenia in ambulatory patients with heart
failure with preserved ejection fraction (HFpEF) and its relation to reduced exercise capacity …

Respiratory and/or limb muscle dysfunction, which are frequently observed in chronic
obstructive pulmonary disease (COPD) patients, contribute to their disease prognosis …

COPD is associated with a progressive loss of muscle mass and function. However, there is
an unmet need to define and standardise methods to estimate the prevalence of sarcopenia …