Cartilage consists of chondrocytes and a special extracellular matrix (ECM) having unique
biochemical, biophysical, and biomechanical properties that play a critical role in the …

Materials at the nanoscale offer numerous avenues to be explored and exploited in diverse
realms. Among others, proteinaceous biomaterials such as silk hold immense prospects in …

Natupolymer-based scaffolds can increase cell affinity to biomaterials and improve cell
responses. Silk fibroin, chitosan and gelatin that mimic the properties of natural extra-cellular …

For effective treatment of infected bone, it is essential to use local drug delivery systems with
the ability to deliver both antibiotics and osteoinductive factors. Herein, a pH-sensitive silk …

Degenerated cartilage tissues remain a burgeoning issue to be tackled, while bioactive
engineering products available for optimal cartilage regeneration are scarce. In the present …

Engineering skin substitutes represent a prospective source of advanced therapy in
repairing severe traumatic wounds. Sodium alginate (SA) and silk fibroin (SF) are natural …

Glycosaminoglycans (GAG) are long, linear polysaccharides that display a wide range of
relevant biological roles. Particularly, in the extracellular matrix (ECM) GAG specifically …

In natural cartilage tissues, chondrocytes are linked to extracellular matrix (ECM) through
cell-surface binding proteins. Surface modification of gelatin can provide a new generation …

This study describes a drug-loaded porous hydrogel for delivery of vancomycin. Hydrogels
based on chitosan (CS), Polyvinyl alcohol (PVA) and Polyethylene glycol (PEG) were …

Drug delivery for treatment of chronic diseases relies on the effective delivery of payload
materials into the target cells in a long-term release. In this context, the present study …