A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation

M Aas, P Dazzan, V Mondelli, I Melle… - Frontiers in …, 2014 - frontiersin.org
Objective: To carry out a systematic review of the literature addressing cognitive functions in
first-episode psychosis (FEP), divided into domains. Although this is not a full “cognitive …

Duration of untreated illness as a key to early intervention in schizophrenia: a review

A Murru, B Carpiniello - Neuroscience letters, 2018 - Elsevier
The first psychotic episode is classically viewed as a critical period which management is
important in determining the long-term outcome of the schizophrenia (SCZ). For this reason …

Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis

WJ Brewer, SM Francey, SJ Wood… - American Journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: While cognitive deficits are frequently reported in psychotic disorders, it is
unclear whether these impairments predate the onset of illness and to what extent they are …

Neurobiological highlights of cognitive impairment in psychiatric disorders

A Morozova, Y Zorkina, O Abramova… - International Journal of …, 2022 - mdpi.com
This review is focused on several psychiatric disorders in which cognitive impairment is a
major component of the disease, influencing life quality. There are plenty of data proving that …

Real-world cognitive—and metacognitive—dysfunction in schizophrenia: a new approach for measuring (and remediating) more “right stuff”

D Koren, LJ Seidman, M Goldsmith… - Schizophrenia …, 2006 - academic.oup.com
While the role of impaired cognition in accounting for functional outcome in schizophrenia is
generally established by now, the overlap is far from complete. Moreover, little is known …

Duration of untreated psychosis: impact on 2-year outcome

J Addington, S Van Mastrigt, D Addington - Psychological medicine, 2004 - cambridge.org
Background. The duration of untreated psychosis has been postulated to be a predictor of
clinical outcome in schizophrenia. Although several prospective studies support the …

Neurocognitive dysfunction in first-episode psychosis: correlates with symptoms, premorbid adjustment, and duration of untreated psychosis

BR Rund, I Melle, S Friis, TK Larsen… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: The authors examined the relationship of neurocognitive function with duration
of untreated psychosis, premorbid illness factors, and clinical symptoms to determine …

Assessing cognitive function in clinical trials of schizophrenia

JH Barnett, TW Robbins, VC Leeson… - Neuroscience & …, 2010 - Elsevier
Cognitive dysfunction in schizophrenia is an important target for novel therapies. Effectively
measuring the cognitive effects of compounds in clinical trials of schizophrenia could be a …

From the psychosis prodrome to the first-episode of psychosis: No evidence of a cognitive decline

RE Carrión, DJ Walder, AM Auther… - Journal of psychiatric …, 2018 - Elsevier
Cognitive deficits have an important role in the neurodevelopment of schizophrenia and
other psychotic disorders. However, there is a continuing debate as to whether cognitive …

The course of cognitive functioning in first episode psychosis: changes over time and impact on outcome

J Addington, H Saeedi, D Addington - Schizophrenia research, 2005 - Elsevier
This three year longitudinal study examined the cognitive performance of 247 individuals
who recently presented with a first episode of psychosis. Using a comprehensive battery of …