On-line preconcentration is one of the aspects of analytical method development using
capillary electrophoretic techniques. The choice of the sample matrix alone can significantly …

An overview of the use of CE‐MS in the field of metabolomics is provided. Metabolomics is
concerned with the comprehensive analysis of endogenous low‐molecular‐weight …

Proteome analysis is now emerging as key technology for deciphering biological processes
and the discovery of biomarkers for diseases from tissues and body fluids. The complexity …

Noninvasive diagnosis of kidney diseases and assessment of the prognosis are still
challenges in clinical nephrology. Definition of biomarkers on the basis of proteome …

Since its introduction in 1987, capillary electrophoresis‐mass spectrometry (CE‐MS) has
developed to a well accepted multidimensional analytical approach complementary and/or …

CE‐MS is a successful proteomic platform for the definition of biomarkers in different body
fluids. Besides the biomarker defining experimental parameters, CE migration time and …

The on-line coupling of capillary electrophoresis (CE) with electrospray-time-of-flight mass
spectrometry (MS) has been used to obtain patterns of peptides and proteins present in the …

The field of clinical proteomics offers opportunities to identify new disease biomarkers in
body fluids, cells and tissues. These biomarkers can be used in clinical applications for …

Mass spectrometry (MS) has become a key tool for the characterization of biologically
relevant molecules in the last decade. Due to the complexity of most biological samples an …

Renal disease in patients with Type II diabetes is the leading cause of terminal renal failure
and a major healthcare problem. Hence early identification of patients prone to develop this …