The design and operation issues for reactive distillation systems are considerably more
complex than those involved for either conventional reactors or conventional distillation …

Reactive distillation process, a representative process intensification technology, has been
widely applied in the chemical industry. However, due to the strong interaction between …

A mixed integer nonlinear programming (MINLP) model is presented for synthesizing
reactive distillation columns when chemical reaction equilibrium cannot be assured. The …

We introduce a new set of composition variables for treating phase equilibria in
multicomponent, multi-reaction systems with or without inert components present. These …

The batch distillation process has existed for many centuries. It is perhaps the oldest
technology for separating or purifying liquid mixtures and is the most frequently used …

The equations describing the simple distillation of homogeneous reactive mixtures are
derived, and residue curve maps are computed for ideal and non-ideal systems. These …

An algorithm (M-SIMPSA) suitable for the optimization of mixed integer non-linear
programming (MINLP) problems is presented. A recently proposed continuous non-linear …

A new set of transformed composition variables is introduced to simplify the design
equations for single-feed, multicomponent reactive distillation columns. Based onthese …

We discuss the impact over the past 40 years of process systems thinking on the design of
chemical processes. We first explore the rich set of issues related to process design, only …

This paper presents a review of advances that have taken place in the mathematical
programming approach to process design and synthesis. A review is first presented on the …