Tailored functionalization of natural phenols to improve biological activity
Phenols are widespread in nature, being the major components of several plants and
essential oils. Natural phenols' anti-microbial, anti-bacterial, anti-oxidant, pharmacological …
essential oils. Natural phenols' anti-microbial, anti-bacterial, anti-oxidant, pharmacological …
The recent discovery of a promising pharmacological scaffold derived from carvacrol: A review
Carvacrol, called CA, is a dynamic phytoconstituent characterized by a phenol ring
abundantly sourced from various natural reservoirs. This versatile scaffold serves as a …
abundantly sourced from various natural reservoirs. This versatile scaffold serves as a …
Synthesis and characterization of a novel schiff base of 1, 2-diaminopropane with substituted salicyaldehyde and its transition metal complexes: Single crystal …
A novel schiff base H2L derived from simple condensation of 2-hydroxy-6-isopropyl-3-
methyl benzaldehyde and 1, 2-diaminopropane in 2: 1 M ratio and its [MnL],[CoL] and [NiL] 2 …
methyl benzaldehyde and 1, 2-diaminopropane in 2: 1 M ratio and its [MnL],[CoL] and [NiL] 2 …
Synthesis, characterization, biochemical, and molecular modeling studies of carvacrol‐based new thiosemicarbazide and 1, 3, 4‐thiadiazole derivatives
T Alagöz, FG Çalişkan, HG Bilgiçli… - Archiv der …, 2023 - Wiley Online Library
A series of carvacrol‐based thiosemicarbazide (3a–e) and 1, 3, 4‐thiadiazole‐2‐amine (4a–
e) were designed and synthesized for the first time. The structures were characterized by …
e) were designed and synthesized for the first time. The structures were characterized by …
Synthesis, DFT calculations, and molecular docking study of acetohydrazide‐based sulfonamide derivatives as paraoxonase 1 inhibitors
Abstract Paraoxonase 1 (PON1), an esterase linked to high‐density lipoprotein (HDL), is
known to have strong antioxidant and anti‐cardiovascular properties. In this study, eleven …
known to have strong antioxidant and anti‐cardiovascular properties. In this study, eleven …
Antifungal activities of natural products and their hybrid molecules
V Khwaza, BA Aderibigbe - Pharmaceutics, 2023 - mdpi.com
The increasing cases of drug resistance and high toxicity associated with the currently used
antifungal agents are a worldwide public health concern. There is an urgent need to develop …
antifungal agents are a worldwide public health concern. There is an urgent need to develop …
Synthesis, antimicrobial and antioxidant activity of pyrazole based sulfonamide derivatives
JR Badgujar, DH More, JS Meshram - Indian journal of microbiology, 2018 - Springer
A series of new sulfonamides have been synthesized from Ampyrone with different benzene
sulfonyl chlorides to yield the N-1, 5-dimethyl-3-oxo-2-phenyl-2, 3-dihydro-1 H-pyrazol-4-yl) …
sulfonyl chlorides to yield the N-1, 5-dimethyl-3-oxo-2-phenyl-2, 3-dihydro-1 H-pyrazol-4-yl) …
Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids
JD Rajput, SD Bagul, UD Pete, CM Zade, SB Padhye… - Molecular Diversity, 2018 - Springer
Carvacrol, thymol and eugenol belong to a class of naturally presenting phenols with a ten-
carbon unit, which are present in essential oils of many plants. These versatile molecules …
carbon unit, which are present in essential oils of many plants. These versatile molecules …
Synthesis, characterizations, biological activities and docking studies of novel dihydroxy derivatives of natural phenolic monoterpenoids containing azomethine …
JD Rajput, SD Bagul, AA Hosamani, MM Patil… - Research on Chemical …, 2017 - Springer
In the present work, we report the synthesis of six new azomethine linkage containing
dihydroxy derivatives of carvacrol, thymol, and eugenol. All the synthesized derivatives have …
dihydroxy derivatives of carvacrol, thymol, and eugenol. All the synthesized derivatives have …
Design, synthesis, crystal structure, and in vitro antibacterial activities of sulfonamide derivatives bearing the 4-aminoquinazoline moiety
S Wan, N Wu, Y Yan, Y Yang, G Tian, L An, X Bao - Molecular Diversity, 2023 - Springer
A total of 66 sulfonamide derivatives bearing the 4-aminoquinazoline moiety were designed
and synthesized, and their structures were fully characterized by 1H NMR, 13C NMR, and …
and synthesized, and their structures were fully characterized by 1H NMR, 13C NMR, and …