Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened
247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in …

SARS-CoV-2 is evolving with mutations in the receptor binding domain (RBD) being of
particular concern. It is important to know how much cross-protection is offered between …

The global decline in malaria has stalled, emphasizing the need for vaccines that induce
durable sterilizing immunity. Here we optimized regimens for chemoprophylaxis vaccination …

Immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ) in
PfSPZ Vaccine, has provided better vaccine efficacy (VE) against controlled human malaria …

Background Malaria elimination requires interruption of the highly efficient transmission of
Plasmodium parasites by mosquitoes. TB31F is a humanised monoclonal antibody that …

Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

In 1967, pioneering work by Ruth Nussenzweig demonstrated for the first time that irradiated
sporozoites of the rodent malaria parasite Plasmodium berghei protected mice against a …

Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Vaccination with infectious Plasmodium falciparum (Pf) sporozoites (SPZ) administered with
antimalarial drugs (PfSPZ-CVac), confers superior sterilizing protection against infection …