Macrophage plasticity and atherosclerosis therapy

P Lin, HH Ji, YJ Li, SD Guo - Frontiers in molecular biosciences, 2021 - frontiersin.org
Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

Macrophage polarization and plasticity in systemic lupus erythematosus

MM Ahamada, Y Jia, X Wu - Frontiers in immunology, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune disease that attacks almost every
organ. The condition mostly happens to adults but is also found in children, and the latter …

TRAIL-expressing cell membrane nanovesicles as an anti-inflammatory platform for rheumatoid arthritis therapy

Y Shi, F Xie, P Rao, H Qian, R Chen, H Chen… - Journal of controlled …, 2020 - Elsevier
Rheumatoid arthritis (RA) is one of the most common chronic autoimmune diseases.
Although the progress made with current clinical use of biologic disease-modifying …

[HTML][HTML] Novel insight on the role of Macrophages in atherosclerosis: Focus on polarization, apoptosis and efferocytosis

Y Xie, H Chen, P Qu, X Qiao, L Guo, L Liu - International …, 2022 - Elsevier
Atherosclerosis (AS) is the main pathological basis of cardiovascular diseases, which is
mainly characterized by lipid deposition and inflammatory response. Macrophages (MΦ), as …

[HTML][HTML] Trained immunity and inflammation in rheumatic diseases

M Badii, O Gaal, RA Popp, TO Crișan, LAB Joosten - Joint Bone Spine, 2022 - Elsevier
Background Rheumatic diseases include a variety of autoimmune and autoinflammatory
conditions that are characterised by musculoskeletal involvement and systemic disease …

Macrophage: key player in the pathogenesis of autoimmune diseases

S Yang, M Zhao, S Jia - Frontiers in Immunology, 2023 - frontiersin.org
The macrophage is an essential part of the innate immune system and also serves as the
bridge between innate immunity and adaptive immune response. As the initiator and …

Circulating extracellular vesicles and rheumatoid arthritis: a proteomic analysis

M Alghamdi, SA Alamry, SM Bahlas… - Cellular and Molecular …, 2022 - Springer
Circulating extracellular vesicles (EVs) are membrane-bound nanoparticles secreted by
most cells for intracellular communication and transportation of biomolecules. EVs carry …

The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus

F Zhang, B Zhang, H Ding, X Li, X Wang… - Advanced …, 2023 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with abnormal
activation of the immune system. Recent attention is increasing about how aberrant lipid and …

Update on the role of extracellular vesicles in rheumatoid arthritis

H Miao, F Wang, S Lin, Z Chen - Expert Reviews in Molecular …, 2022 - cambridge.org
Rheumatoid arthritis (RA) is a heterogeneous autoimmune disorder that leads to severe joint
deformities, negatively affecting the patient's quality of life. Extracellular vesicles (EVs) …

Endoplasmic reticulum stress in systemic lupus erythematosus and lupus nephritis: potential therapeutic target

HY Li, LF Huang, XR Huang, D Wu… - Journal of …, 2023 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Approximately one‐
third to two‐thirds of the patients with SLE progress to lupus nephritis (LN). The …