Zinc coordination complexes as anticancer agents

M Pellei, F Del Bello, M Porchia, C Santini - Coordination Chemistry …, 2021 - Elsevier
Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …

Metal complexes incorporating tridentate ONO pyridyl hydrazone Schiff base ligands: Crystal structure, characterization and applications

H Kargar, M Fallah-Mehrjardi, KS Munawar - Coordination Chemistry …, 2024 - Elsevier
Schiff bases are an extensive group of materials which have a carbon–nitrogen double bond
(–C= N–). The present review gives a perspective on this class of compounds by …

Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

In vitro cytotoxicity activity of novel Schiff base ligand–lanthanide complexes

K Andiappan, A Sanmugam, E Deivanayagam… - Scientific reports, 2018 - nature.com
A Schiff base ligand (SBL), N2, N3-bis (anthracen-9-ylmethylene) pyridine-2, 3-diamine, was
synthesized through the condensation of 2, 6-diaminopyridine and anthracene-9 …

Titanium (IV) complex containing ONO-tridentate Schiff base ligand: Synthesis, crystal structure determination, Hirshfeld surface analysis, spectral characterization …

H Kargar, M Fallah-Mehrjardi… - Journal of molecular …, 2021 - Elsevier
A novel titanium (IV) complex (Ti (L) 2) with tridentate ONO-donor Schiff base ligand (H2L
(E)-4-amino-N'-(3-ethoxy-2-hydroxybenzylidene) benzohydrazide) was synthesized. The …

Designing anticancer copper (II) complexes by optimizing 2-pyridine-thiosemicarbazone ligands

J Deng, P Yu, Z Zhang, J Wang, J Cai, N Wu… - European Journal of …, 2018 - Elsevier
To develop potential next-generation metal anticancer agents, we designed and
synthesised five Cu (II) 2-pyridine-thiosemicarbazone complexes by modifying the hydrogen …

Synthesis, DNA binding, antibacterial and anticancer properties of two novel water-soluble copper (II) complexes containing gluconate

DH Cai, CL Zhang, QY Liu, L He, YJ Liu… - European Journal of …, 2021 - Elsevier
In this paper, two new Cu (II) complexes,[Cu (Gluc)(HPB)(H 2 O)] Gluc (CuG1) and [Cu
(Gluc)(HPBC)(H 2 O)] Gluc (CuG2)(where HPB= 2-(2′-pyridyl) benzimidazole, HPBC= 5 …

Synthesis, structural studies, interaction with DNA/HSA and antitumor evaluation of new Cu (II) complexes containing 2-(1 H-imidazol-2-yl) pyridine and amino acids

DH Cai, BH Chen, QY Liu, XY Le, L He - Dalton Transactions, 2022 - pubs.rsc.org
Copper complexes are considered as potential candidates for anticancer therapy and
medical applications. In this paper, three new Cu (II) complexes,[Cu (IPY) 2](ClO4) 2· H2O …

Design, synthesis and characterization of novel Ni (II) and Cu (II) complexes as antivirus drug candidates against SARS-CoV-2 and HIV virus

M Choudhary - Journal of Molecular Structure, 2022 - Elsevier
This paper describes the structure-based design, synthesis and anti-virus effect of two new
coordination complexes, a Ni (II) complex [Ni (L) 2](1) and a Cu (II) complex [Cu (L) 2](2) of …

Copper (II) complexes containing natural flavonoid pomiferin show considerable in vitro cytotoxicity and anti-inflammatory effects

J Vančo, Z Trávníček, J Hošek, T Malina… - International Journal of …, 2021 - mdpi.com
A series of new heteroleptic copper (II) complexes of the composition [Cu (L)(bpy)] NO3·
2MeOH (1),[Cu (L)(dimebpy)] NO3· 2H2O (2),[Cu (L)(phen)] NO3· 2MeOH (3),[Cu …