Tumor cells migrate through changing microenvironments of diseased and healthy tissue,
making their migration particularly challenging to describe. To better understand this …

Significant changes in cell stiffness, contractility, and adhesion, ie, mechanotype, are
observed during a variety of biological processes. Whether cell mechanics merely change …

Proliferation and invasion are two key drivers of tumor growth that are traditionally
considered independent multicellular processes. However, these processes are intrinsically …

Neuronal circuits are hallmarks of complex decision-making processes in the animal world.
How animals without neurons process information and respond to environmental cues …

Mesenchymal condensation is a prevalent morphogenetic transition that is essential in
chondrogenesis. However, the current understanding of condensation mechanisms is …

Cell proliferation and invasion are two key drivers of tumor progression and are traditionally
considered two independent cellular processes regulated by distinct pathways. Through in …

Protrusions are one of the structures that cells use to sense their surrounding environment in
a probing and exploratory manner as well as to communicate with other cells. In particular …

Neural crest cells are embryonic stem cells that migrate throughout embryos and, at different
target locations, give rise to the formation of a variety of tissues and organs. The directional …

Cells migrating in clusters play a significant role in a number of biological processes such as
embryogenesis, wound healing, and tumor metastasis during cancer progression. A variety …

The high mortality rate of cancer is associated with metastasis of the primary tumor and can
drastically reduce a patient's 5-year survival rate. Patient outcomes typically scale with the …