The not-so-good, the bad and the ugly: HPV E5, E6 and E7 oncoproteins in the orchestration of carcinogenesis
O Basukala, L Banks - Viruses, 2021 - mdpi.com
Infection with HPV starts with the access of the viral particles to basal cells in the epidermis,
potentially via microtraumas to the skin. The basal cells are able to keep away these …
potentially via microtraumas to the skin. The basal cells are able to keep away these …
The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications
SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway
The role that human papillomavirus (HPV) oncogenes play in suppressing responses to
immunotherapy in cancer deserves further investigation. In particular, the effects of HPV E5 …
immunotherapy in cancer deserves further investigation. In particular, the effects of HPV E5 …
Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors
TP Schrank, A Kothari, WH Weir… - Proceedings of the …, 2023 - National Acad Sciences
We analyzed transcriptional data from 104 HPV+ (Human papillomavirus) HNSCC (head
and neck squamous cell carcinoma) tumors together with two publicly available sources to …
and neck squamous cell carcinoma) tumors together with two publicly available sources to …
Protein kinase CK2–diverse roles in cancer cell biology and therapeutic promise
JH Trembley, BT Kren, M Afzal, GA Scaria… - Molecular and cellular …, 2023 - Springer
The association of protein kinase CK2 (formerly casein kinase II or 2) with cell growth and
proliferation in cells was apparent at early stages of its investigation. A cancer-specific role …
proliferation in cells was apparent at early stages of its investigation. A cancer-specific role …
[HTML][HTML] HPV infections—classification, pathogenesis, and potential new therapies
B Mlynarczyk-Bonikowska, L Rudnicka - International Journal of …, 2024 - mdpi.com
To date, more than 400 types of human papillomavirus (HPV) have been identified. Despite
the creation of effective prophylactic vaccines against the most common genital HPVs, the …
the creation of effective prophylactic vaccines against the most common genital HPVs, the …
Circulating human papillomavirus DNA in head and neck squamous cell carcinoma: possible applications and future directions
Simple Summary Circulating human papillomavirus DNA is a promising tool in the
management of HPV-positive oropharyngeal cancer. The potential use of this tool will …
management of HPV-positive oropharyngeal cancer. The potential use of this tool will …
Emerging paradigms: unmasking the role of oxidative stress in HPV-induced carcinogenesis
A Letafati, Z Taghiabadi, N Zafarian, R Tajdini… - Infectious Agents and …, 2024 - Springer
The contribution of the human papillomavirus (HPV) to cancer is significant but not
exclusive, as carcinogenesis involves complex mechanisms, notably oxidative stress …
exclusive, as carcinogenesis involves complex mechanisms, notably oxidative stress …
Reduced MHC Class I and II Expression in HPV− Negative vs. HPV− Positive Cervical Cancers
Cervical cancer (CC) is the second most common cancer in women worldwide and the
fourth leading cause of cancer-associated death in women. Although human papillomavirus …
fourth leading cause of cancer-associated death in women. Although human papillomavirus …
Extrachromosomal DNA in HPV-mediated oropharyngeal cancer drives diverse oncogene transcription
Purpose: Human papillomavirus (HPV) plays a major role in oncogenesis and circular
extrachromosomal DNA (ecDNA) is found in many cancers. However, the relationship …
extrachromosomal DNA (ecDNA) is found in many cancers. However, the relationship …