Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

During Parkinson's disease (PD), both the central nervous system (CNS) and peripheral
nervous system (PNS) are affected. In parallel, innate immune cells respond early to …

Microglia-mediated neuroinflammation and mitochondrial dysfunction play critical role in the
pathogenic process of Parkinson's disease (PD). Mitophagy plays central role in …

Neuroinflammation has been implicated in the initiation and progression of several central
nervous system (CNS) disorders, including Alzheimer's disease, Parkinson's disease …

Parkinson's disease (PD) is a neurodegenerative disease due to the degeneration of
dopaminergic neurons (DNs) in the substantia nigra (SN). The liver X receptor (LXR) is …

Epigallocatechin 3-gallate (EGCG), an abundant polyphenolic component derived from
green tea extract, possesses versatile bioactivities that can combat many diseases. During …

Microglia-mediated neuroinflammation plays a crucial role in the pathogenesis of
Parkinson's disease (PD). Triggering receptor expressed on myeloid cells 2 (TREM2) …

Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by selective loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) region of the midbrain …

Our understanding of the role of innate and adaptive immune cell function in brain health
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …