The most neglected aspects of Chagas disease (CD) have been patient care and treatment.
Despite recent progress in the development of potentially improved drugs, there is no …

There are approximately 7.8 million people in Latin America, including Chile, who suffer
from Chagas disease and another 28 million who are at risk of contracting it. Chagas is …

Monocytes are classified according to their CD14 and CD16 expression into classical
(reparative), intermediate (inflammatory), and non-classical. This study assessed the …

Introduction• Chagas' disease• Chemotherapy• Immune response in experimental T. cruzi
infection• Immune response in human beings infected with T. cruzi• Immune response in the …

Herein we have employed an alternative strategy to assess the cytokine patterns of
circulating leukocytes and correlate dominant cytokine profiles with indeterminate‐IND and …

Chronic Chagas cardiomyopathy (CCC) is the most frequent and severe form of Chagas
disease, a neglected tropical illness caused by the protozoan Trypanosoma cruzi, and the …

Chagas disease is a chronic infection caused by Trypanosoma cruzi, an intracellular
protozoan parasite. Chronic chagasic patients (CCPs) have dysfunctional CD8+ T cells that …

Symptomatic chronic Chagas disease affects up to 40% of patients infected with
Trypanosoma cruzi. The lack of reliable early markers of cure after therapy hinders disease …

Background: In contrast to adults, Trypanosoma cruzi-infected children have more broadly
functional Trypanosoma cruzi-specific T cells, and the total T-cell compartment exhibits …

Background We previously showed that newborns congenitally infected with Trypanosoma
cruzi (M+ B+) display a strong type 1 parasite-specific T cell immune response, whereas …