The shortcomings of qualitative visual assessment have led to the development of computer-
based tools to characterise and quantify disease on high-resolution computed tomography …

The advent of quantitative computed tomography (QCT) and artificial intelligence (AI) using
high-resolution computed tomography data has revolutionised the way interstitial diseases …

Tobacco smoking is an established cause of pulmonary disease whose contribution to
interstitial lung disease (ILD) is incompletely characterized. We hypothesized that compared …

Rationale: Cough is a key symptom in patients with fibrotic interstitial lung disease (ILD).
Objectives: This study evaluated the prevalence, longitudinal change, associations, and …

The concept of progressive pulmonary fibrosis (PPF) has been introduced to predict the
diverse prognosis of interstitial lung disease (ILD). However, the incidence and effect of PPF …

Background Monocyte-derived alveolar macrophages (Mo_AMs) are increasingly
recognised as potential pathogenic factors for idiopathic pulmonary fibrosis (IPF). While …

Interstitial lung diseases (ILDs) are a heterogeneous group of disorders that are classified
together because of similar clinical, physiologic, radiographic, and pathologic …

Interstitial lung diseases (ILDs) are a diverse collection of lung disorders sharing similar
features, such as inflammation and fibrosis. The diagnosis and management of ILD require a …

Despite progress in elucidation of disease mechanisms, identification of risk factors,
biomarker discovery, and the approval of two medications to slow lung function decline in …

Background Progressive pulmonary fibrosis (PFF) is of substantial interest for novel
pharmacotherapy discovery, but little is known about clinical trial eligibility criteria. We …