Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) identified in 2003
infected∼ 8000 people in 26 countries with 800 deaths, which was soon contained and …

With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

In this review, we collected 1765 severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) M-pro inhibitors from the bibliography and other sources, such as the COVID …

The current pandemic caused by the COVID-19 disease has reached everywhere in the
world and has affected every aspect of our lives. As of the current data, the World Health …

Alterations in viral fitness cannot be inferred from only mutagenesis studies of an isolated
viral protein. To-date, no systematic analysis has been performed to identify mutations that …

The highly transmissible variants of SARS-CoV-2, the causative pathogen of the COVID-19
pandemic, bring new waves of infection worldwide. Identification of effective therapeutic …

Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global crisis. Clinical candidates with …

During the replication process of SARS-CoV-2, the main protease of the virus [3-
chymotrypsin-like protease (3CLpro)] plays a pivotal role and is essential for the life cycle of …

Abstract The coronavirus disease 2019 (COVID-19) pandemic is fading, however its
etiologic agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues …