Inhaled liposomal antimicrobial delivery in lung infections

M Bassetti, A Vena, A Russo, M Peghin - Drugs, 2020 - Springer
The management of difficult-to-treat acute and chronic respiratory infections (infections in
cystic fibrosis, non-cystic fibrosis bronchiectasis, immunocompromised and mechanically …

Inhaled antibiotics for lower airway infections

BS Quon, CH Goss, BW Ramsey - Annals of the American Thoracic …, 2014 - atsjournals.org
Inhaled antibiotics have been used to treat chronic airway infections since the 1940s. The
earliest experience with inhaled antibiotics involved aerosolizing antibiotics designed for …

In vitro release study of the polymeric drug nanoparticles: development and validation of a novel method

J Weng, HHY Tong, SF Chow - Pharmaceutics, 2020 - mdpi.com
The in vitro release study is a critical test to assess the safety, efficacy, and quality of
nanoparticle-based drug delivery systems, but there is no compendial or regulatory …

Drug release from nanomedicines: selection of appropriate encapsulation and release methodology

SJ Wallace, J Li, RL Nation, BJ Boyd - Drug delivery and translational …, 2012 - Springer
The characterization of encapsulation efficiency and in vitro drug release from nanoparticle-
based formulations often requires the separation of nanoparticles from unencapsulated …

Chitosan nanoparticles making their way to clinical practice: A feasibility study on their topical use for acne treatment

H Abd-Allah, RTA Abdel-Aziz, M Nasr - International journal of biological …, 2020 - Elsevier
Despite the popularity of chitosan as a biodegradable polymer used in a variety of
applications, clinical trials involving chitosan or its nanoparticles are still scarce. Moreover …

Inhaled drug therapy for treatment of tuberculosis

A Misra, AJ Hickey, C Rossi, G Borchard, H Terada… - Tuberculosis, 2011 - Elsevier
The lungs have received attention as a portal for drug delivery in tuberculosis (TB) from
researchers addressing diverse objectives. These include:(a) targeting alveolar …

Evaluation of paeonol-loaded transethosomes as transdermal delivery carriers

ZX Chen, B Li, T Liu, X Wang, Y Zhu, L Wang… - European journal of …, 2017 - Elsevier
Paeonol shows effective anti-allergic, anti-inflammatory and analgesic activities. However,
because of its poor solubility in water and high volatility at room temperature, the application …

Mesoporous silica nanocarriers as drug delivery systems for anti-tubercular agents: a review

JO Tella, JA Adekoya… - Royal Society Open …, 2022 - royalsocietypublishing.org
The treatment and management of tuberculosis using conventional drug delivery systems
remain challenging due to the setbacks involved. The lengthy and costly treatment regime …

Advances in nanotechnology-based carrier systems for targeted delivery of bioactive drug molecules with special emphasis on immunotherapy in drug resistant …

J Singh, T Garg, G Rath, AK Goyal - Drug delivery, 2016 - Taylor & Francis
From the early sixteenth and seventeenth centuries to the present day of life, tuberculosis
(TB) still is a global health threat with some new emergence of resistance. This type of …

Effects of lipid composition and preparation conditions on physical-chemical properties, technological parameters and in vitro biological activity of gemcitabine-loaded …

M Grazia Calvagno, C Celia, D Paolino… - Current drug …, 2007 - ingentaconnect.com
The effects of lipid composition and preparation conditions on the physicochemical and
technological properties of gemcitabine-loaded liposomes, as well as the in vitro anti …