Prophylactic effects of apigenin against hyperglycemia-associated amnesia via activation of the Nrf2/ARE pathway in zebrafish

B Haridevamuthu, SPRR Nayak, R Murugan… - European Journal of …, 2024 - Elsevier
The escalating focus on ageing-associated disease has generated substantial interest in the
phenomenon of cognitive impairment linked to diabetes. Hyperglycemia exacerbates …

A comprehensive investigation of Clerodendrum Infortunatum Linn. using LC-QTOF-MS/MS metabolomics as a promising anti-alzheimer candidate

F Atef, MA Abdelkawy, BM Eltanany, L Pont… - Scientific Reports, 2025 - nature.com
Alzheimer's disease (AD) poses a global health challenge, demanding innovative
approaches for effective treatments. Clerodendrum infortunatum Linn.(Lamiaceae) is a …

Glutathione-Responsive Nanoplatforms Based on Coordination between Fe3+ and Apigenin for Synergistic Chemo/Chemodynamic Therapy

ZH He, HX Tang, YZ Pan, M Cen… - ACS Applied Nano …, 2024 - ACS Publications
The oxygen consumption during chemodynamic therapy (CDT) can lead to severe cellular
hypoxia, resulting in an increase in the hypoxia inducible factor-1α (HIF-1α) level, which …

Targeting of wnt signalling pathway by small bioactive molecules for the treatment of Alzheimer's disease

A Dutta, P Bhattacharya, P Chutia, A Borah - In Silico Pharmacology, 2024 - Springer
Alzheimer's disease (AD) is the most occurring neurodegenerative disorder that destroys
learning, memory, and thinking skills. Although the pathophysiology of the disease is least …