Atherosclerotic coronary artery disease, which can result in coronary artery stenosis, acute
coronary artery occlusion, and eventually myocardial infarction, is a major cause of morbidity …

Computational models of cardiovascular physiology can inform clinical decision‐making,
providing a physically consistent framework to assess vascular pressures and flow …

An extended Kalman filter estimator for the identification of systemic circulation model
parameters during cardiac ejection and cardiac filling is described. The estimator has been …

Diastolic dysfunction is a common pathology occurring in about one third of patients affected
by heart failure. This condition may not be associated with a marked decrease in cardiac …

The left ventricular assist device (LVAD) is a mechanical device implanted in patients with
congestive heart failure to assist the heart in pumping blood through the circulatory system …

In this paper, the current published knowledge about smart and adaptive engineering
systems in medicine is reviewed. The achievements of frontier research in this particular …

A cardiovascular parameter estimator to identify the systemic vascular parameters was
developed using an extended Kalman filter (EKF) algorithm. Measurements from a …

Advancement of implanted left ventricular assist device (LVAD) technology includes modern
sensing and control methods to enable online diagnostics and monitoring of patients using …

The traditional research activities of the Biomechanics Group at the Helmholtz-Institute,
which were based on heart valve research, have extended into the field of blood pumps …

The development of an electromechanically driven total artificial heart (Helmholtz‐TAH) was
initiated in 1990. Anatomical fitting, biocompatibility, and automatic physiologic adaptation of …