Listeria monocytogenes is a Gram-positive bacterium that is often used to study the
mammalian immune response to infection because it is easy to culture, is relatively safe to …

The Gram-positive facultative intracellular bacterium Listeria monocytogenes is a model
pathogen for elucidating important mechanisms of the immune response. Infection of mice …

Dendritic cells (DCs) present microbial antigens to T cells and provide inflammatory signals
that modulate T cell differentiation. While the role of DCs in adaptive immunity is well …

Salmonella typhimurium is considered a facultative intracellular pathogen, but its
intracellular location in vivo has not been demonstrated conclusively. Here we describe the …

Rapid removal of pathogens from the circulation by secondary lymphoid organs is
prerequisite for successful control of infection. Blood-borne Ags are trapped mainly in the …

CD8α+ dendritic cells (DCs) prime cytotoxic T lymphocytes during viral infections and
produce interleukin-12 in response to pathogens. Although the loss of CD8α+ DCs in …

Listeriosis is a severe human and animal disease caused by two species of pathogenic
bacteria from the genus Listeria, L. monocytogenes and L. ivanovii. In humans, listeriosis is …

The immune response to infection can vary markedly in different organs of the same animal.
In some organs, the infection can resolve with subsequent immunity to re-infection, whereas …

Resistance to infection with Listeria monocytogenes involves a series of cellular interactions,
many of which are carried on by cytokines. Macrophages. NK cells and neutrophils …

This study shows that neutrophils are critical for combating experimental systemic infections
of mice by the bacterial pathogens Listeria monocytogenes, Salmonella typhimurium, and …