Brown and beige adipocytes can catabolize stored energy to generate heat, and this distinct
capacity for thermogenesis could be leveraged as a therapy for metabolic diseases like …

Non-shivering thermogenesis in brown adipose tissue is mediated by uncoupling protein 1
(UCP1), which provides a carefully regulated proton re-entry pathway across the …

Mitochondrial uncoupling protein 1 (UCP1) gives brown adipose tissue of mammals its
specialized ability to burn calories as heat for thermoregulation. When activated by fatty …

Extensively revised, the fourth edition of this highly successful book takes into account the
many newly determined protein structures that provide molecular insight into chemiosmotic …

Summary That uncoupling protein 1 (UCP1) is the sole mediator of adipocyte thermogenesis
is a conventional viewpoint that has primarily been inferred from the attenuation of the …

Mitochondria couple respiration to ATP synthesis through an electrochemical proton
gradient. Proton leak across the inner membrane allows adjustment of the coupling …

Mitochondria of all tissues convert various metabolic substrates into two forms of energy:
ATP and heat. Historically, the primary focus of research in mitochondrial bioenergetics was …

Recent studies suggest that thermogenesis in brown adipose tissue has an important role in
the regulation of energy balance1–7. Thermogenesis is effected by noradrenaline released …

Effect of fatty acids on energy coupling processes in mitochondria - ScienceDirect Skip to
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Thermogenesis in brown adipose tissue (BAT) is attributed to uncoupling of respiration
which is caused by a speci¢ c component located in the inner mitochondrial membrane, the …