Ten years of next-generation sequencing technology

EL Van Dijk, H Auger, Y Jaszczyszyn, C Thermes - Trends in genetics, 2014 - cell.com
Ten years ago next-generation sequencing (NGS) technologies appeared on the market.
During the past decade, tremendous progress has been made in terms of speed, read …

Bacillus thuringiensis Toxins: An Overview of Their Biocidal Activity

L Palma, D Muñoz, C Berry, J Murillo, P Caballero - Toxins, 2014 - mdpi.com
Bacillus thuringiensis (Bt) is a Gram positive, spore-forming bacterium that synthesizes
parasporal crystalline inclusions containing Cry and Cyt proteins, some of which are toxic …

The cityscapes dataset for semantic urban scene understanding

M Cordts, M Omran, S Ramos… - Proceedings of the …, 2016 - openaccess.thecvf.com
Visual understanding of complex urban street scenes is an enabling factor for a wide range
of applications. Object detection has benefited enormously from large-scale datasets …

The real cost of sequencing: scaling computation to keep pace with data generation

P Muir, S Li, S Lou, D Wang, DJ Spakowicz, L Salichos… - Genome biology, 2016 - Springer
As the cost of sequencing continues to decrease and the amount of sequence data
generated grows, new paradigms for data storage and analysis are increasingly important …

Corset: enabling differential gene expression analysis for de novoassembled transcriptomes

NM Davidson, A Oshlack - Genome biology, 2014 - Springer
Next generation sequencing has made it possible to perform differential gene expression
studies in non-model organisms. For these studies, the need for a reference genome is …

Sequence assembly demystified

N Nagarajan, M Pop - Nature Reviews Genetics, 2013 - nature.com
Advances in sequencing technologies and increased access to sequencing services have
led to renewed interest in sequence and genome assembly. Concurrently, new applications …

Historical perspective, development and applications of next-generation sequencing in plant virology

M Barba, H Czosnek, A Hadidi - Viruses, 2014 - mdpi.com
Next-generation high throughput sequencing technologies became available at the onset of
the 21st century. They provide a highly efficient, rapid, and low cost DNA sequencing …

A fast and agnostic method for bacterial genome-wide association studies: Bridging the gap between k-mers and genetic events

M Jaillard, L Lima, M Tournoud, P Mahé… - PLoS …, 2018 - journals.plos.org
Genome-wide association study (GWAS) methods applied to bacterial genomes have
shown promising results for genetic marker discovery or detailed assessment of marker …

Assemblathon 1: a competitive assessment of de novo short read assembly methods

D Earl, K Bradnam, JS John, A Darling, D Lin… - Genome …, 2011 - genome.cshlp.org
Low-cost short read sequencing technology has revolutionized genomics, though it is only
just becoming practical for the high-quality de novo assembly of a novel large genome. We …

Effects of GC Bias in Next-Generation-Sequencing Data on De Novo Genome Assembly

YC Chen, T Liu, CH Yu, TY Chiang, CC Hwang - PloS one, 2013 - journals.plos.org
Next-generation-sequencing (NGS) has revolutionized the field of genome assembly
because of its much higher data throughput and much lower cost compared with traditional …