Transition-metal-catalyzed C–H bond activation for the formation of C–C bonds in complex molecules

JH Docherty, TM Lister, G Mcarthur, MT Findlay… - Chemical …, 2023 - ACS Publications
Site-predictable and chemoselective C–H bond functionalization reactions offer synthetically
powerful strategies for the step-economic diversification of both feedstock and fine …

Metal-catalysed C–Het (F, O, S, N) and C–C bond arylation

B Zhao, T Rogge, L Ackermann, Z Shi - Chemical Society Reviews, 2021 - pubs.rsc.org
The formation of C–aryl bonds has been the focus of intensive research over the last
decades for the construction of complex molecules from simple, readily available feedstocks …

Electrochemically enabled, nickel-catalyzed dehydroxylative cross-coupling of alcohols with aryl halides

Z Li, W Sun, X Wang, L Li, Y Zhang… - Journal of the American …, 2021 - ACS Publications
As alcohols are ubiquitous throughout chemical science, this functional group represents a
highly attractive starting material for forging new C–C bonds. Here, we demonstrate that the …

Recent advances in metal‐catalyzed functionalization of indoles

K Urbina, D Tresp, K Sipps… - Advanced Synthesis & …, 2021 - Wiley Online Library
Indole is one of the most important heterocycles in organic synthesis, natural products, and
drug discovery. Recently, tremendous advances in the selective functionalization of indoles …

Ruthenium (II)-catalyzed C–H bond activation and functionalization

PB Arockiam, C Bruneau, PH Dixneuf - Chemical reviews, 2012 - ACS Publications
The catalytic functionalization of unreactive C− H bonds has recently brought a revolution in
synthetic methodologies for the production of pharmaceuticals and natural products and for …

Dynamic kinetic cross-electrophile arylation of benzyl alcohols by nickel catalysis

P Guo, K Wang, WJ Jin, H Xie, L Qi… - Journal of the …, 2020 - ACS Publications
Catalytic transformation of alcohols via metal-catalyzed cross-coupling reactions is very
important, but it typically relies on a multistep procedure. We here report a dynamic kinetic …

Phenol-directed C–H functionalization

Z Huang, JP Lumb - ACS Catalysis, 2018 - ACS Publications
Phenols are important starting materials, intermediates, and functional elements of a very
broad range of chemicals and materials. They are large-volume products of benzene …

Transition metal-catalyzed organic reactions in undivided electrochemical cells

C Ma, P Fang, D Liu, KJ Jiao, PS Gao, H Qiu… - Chemical Science, 2021 - pubs.rsc.org
Transition metal-catalyzed organic electrochemistry is a rapidly growing research area
owing in part to the ability of metal catalysts to alter the selectivity of a given transformation …

Bioactive Benzofuran derivatives: A review

H Khanam - European journal of medicinal chemistry, 2015 - Elsevier
In nature's collection of biologically active heterocycles, benzofuran derivatives constitute a
major group. The broad spectrum of pharmacological activity in individual benzofurans …

Unlocking the Friedel-Crafts arylation of primary aliphatic alcohols and epoxides driven by hexafluoroisopropanol

S Zhang, M Vayer, F Noel, VD Vuković, A Golushko… - Chem, 2021 - cell.com
Alcohols and epoxides are arguably ideal electrophiles for the Friedel-Crafts alkylation,
since they are widely available, require no pre-activation, and produce no stoichiometric …