Recent insights into breast cancer incidence trends among four Asian countries using age-period-cohort model

S Mubarik, SS Malik, Z Wang, C Li… - Cancer management …, 2019 - Taylor & Francis
Purpose Breast cancer is one of the rapidly increasing cancers among women and a
significant cause of cancer-related morbidity and mortality worldwide. Therefore, the current …

SNP mutation‐related genes in breast cancer for monitoring and prognosis of patients: a study based on the TCGA database

C Gao, J Zhuang, C Zhou, H Li, C Liu, L Liu… - Cancer …, 2019 - Wiley Online Library
Advances in cancer biology have allowed early diagnosis and more comprehensive
treatment of breast cancer (BC). However, it remains the most common cause of cancer …

Involvement of Xeroderma Pigmentosum Complementation Group G (XPG) in epigenetic regulation of T-Helper (TH) cell differentiation during breast cancer

R Pal, S Rakshit, G Shanmugam, N Paul… - Immunobiology, 2022 - Elsevier
TNFα and IFN-γ secreted by CD4+ T-Helper (TH) cells have antitumor activity followed by
polarisation of TH 1 phenotype in response to IL-12 secreted by dendritic cells, inducing …

A hierarchical age–period–cohort analysis of breast cancer mortality and disability adjusted life years (1990–2015) attributable to modified risk factors among Chinese …

S Mubarik, F Wang, SS Malik, F Shi, Y Wang… - International journal of …, 2020 - mdpi.com
Limited studies quantified the age, period, and cohort effects attributable to different risk
factors on mortality rates (MRs) and disability-adjusted life years (DALYs) due to breast …

XPC as breast cancer susceptibility gene: evidence from genetic profiling, statistical inferences and protein structural analysis

SS Malik, A Zia, S Rashid, S Mubarik, N Masood… - Breast Cancer, 2020 - Springer
Background Gene polymorphisms that affect nucleotide excision repair (NER) pathway may
link with higher susceptibility of breast cancer (BC); however, the significance of these …

Correlation of MSH2 exonic deletions and protein downregulation with breast cancer biomarkers and outcome in Pakistani women/patients

SS Malik, S Mubarik, A Aftab, R Khan… - … Science and Pollution …, 2021 - Springer
Mismatch repair (MMR) pathway is one of the underlying mechanisms of predisposition to
breast cancer (BC). The present study explored the association of MSH2 exonic deletions …

Variants of ERCC5 and the outcome of platinum-based regimens in non-small cell lung cancer: A prospective cohort study

ES Abdalkhalek, LME Wakeel, AA Nagy, NA Sabri - Medical Oncology, 2022 - Springer
Excision repair complementary complex 5 (ERCC5) is an important component in the repair
pathway of platinum-induced damage. The current study evaluated the effect of ERCC5 …

着色性干皮病基因G 组基因多态性与胃癌的相关研究进展

李雯彬, 卢娟娟 - 临床荟萃, 2020 - huicui.hebmu.edu.cn
着色性干皮病基因G 组(xeroderma pigmentosum group G, XPG) 是一种结构特异性内切核酸
酶, 参与核苷酸切除修复(nucleotide excision repair) 和转录, 对于纠正切除修复缺陷至关重要 …

[HTML][HTML] Genetic polymorphism in ERCC5 and breast cancer risk

SS Malik, S Mubarik, M Baig, N Masood… - Molecular Biology …, 2019 - ncbi.nlm.nih.gov
ERCC5 plays crucial role in excision repair DNA damage induced by UV in NER pathway.
Single neuleotide polymorphism in ERCC5 were responsible for different cancers …

Correlation of MLH1 polymorphisms, survival statistics, in silico assessment and gene downregulation with clinical outcomes among breast cancer cases

SS Malik, A Zia, S Mubarik, N Masood, S Rashid… - Molecular Biology …, 2020 - Springer
This study aimed to investigate the role of MLH1 polymorphisms, respective protein structure
prediction, survival analysis, related clinicopathological details and MLH1 expression in …