ABSTRACT PDZ proteins are highly conserved through evolution; the principal function of
this large family of proteins is to assemble protein complexes that are involved in many …

Scribble is a scaffolding protein that regulates key events such as cell polarity,
tumorigenesis and neuronal signalling. Scribble belongs to the LAP family which comprise …

The Envelope protein (E) is one of the four structural proteins encoded by the genome of
SARS‐CoV and SARS‐CoV‐2 Coronaviruses. It is an integral membrane protein, highly …

Cell polarity refers to the asymmetric distribution of biomacromolecules that enable the
correct orientation of a cell in a particular direction. It is thus an essential component for …

The central importance of cell polarity control is emphasized by the frequency with which it is
targeted by many diverse viruses. It is clear that in targeting key polarity control proteins …

The Envelope protein (E) is a structural protein encoded by the genome of SARS-CoV,
SARS-CoV-2 and MERS-CoV Coronaviruses. It is poorly present in the virus but highly …

Discs large membrane-associated guanylate kinase (MAGUK) scaffold protein 1 (DLG1)
plays important roles in cell contact and migration, but its role in antiviral innate immunity is …

hScrib and hDlg belong to the PDZ family of proteins. Since the identification of these highly
phylogenetically conserved scaffolds, an increasing amount of experiments has elucidated …

Abstract PDZ (PSD-95/Dlg/ZO-1) domain-containing proteins constitute a large family of
scaffolds involved in a wide range of cellular tasks, and mainly studied in polarity functions …

Viruses have evolved to interact with their hosts. Some viruses such as human papilloma
virus, dengue virus, SARS-CoV, or influenza virus encode proteins including a PBM that …