The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI

Y Zhou, C Bie, PCM van Zijl, NN Yadav - NMR in biomedicine, 2023 - Wiley Online Library
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …

Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo

PCM van Zijl, K Brindle, H Lu, PB Barker… - Current opinion in …, 2021 - Elsevier
Access to metabolic information in vivo using magnetic resonance (MR) technologies has
generally been the niche of MR spectroscopy (MRS) and spectroscopic imaging (MRSI) …

Whole‐brain amide CEST imaging at 3T with a steady‐state radial MRI acquisition

R Sui, L Chen, Y Li, J Huang, KWY Chan… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To develop a steady‐state saturation with radial readout chemical exchange
saturation transfer (starCEST) for acquiring CEST images at 3 Tesla (T). The polynomial …

The multifaceted roles of the brain glycogen

KH Markussen, M Corti, BJ Byrne… - Journal of …, 2024 - Wiley Online Library
Glycogen is a biologically essential macromolecule that is directly involved in multiple
human diseases. While its primary role in carbohydrate storage and energy metabolism in …

Noise reduction of nuclear magnetic resonance spectroscopy using lightweight deep neural network

H Zhan, Q Fang, J Liu, X Shi, X Chen, Y Huang… - Acta Physico-Chimica …, 2024 - Elsevier
Nuclear magnetic resonance (NMR) spectroscopy serves as a robust non-invasive
characterization technique for probing molecular structure and providing quantitative …

Role of chemical exchange on the relayed nuclear Overhauser enhancement signal in saturation transfer MRI

T Jin, SG Kim - Magnetic resonance in medicine, 2022 - Wiley Online Library
Purpose The pH sensitivity of chemical exchange‐relayed nuclear Overhauser
enhancement (rNOE) signal in a saturation transfer experiment is not fully understood and …

Imaging of sugar‐based contrast agents using their hydroxyl proton exchange properties

L Knutsson, X Xu, PCM van Zijl… - NMR in …, 2023 - Wiley Online Library
The ability of CEST MRI to detect the presence of millimolar concentrations of non‐metallic
contrast agents has made it possible to study, non‐invasively, important biological …

Guanidinium and amide CEST mapping of human brain by high spectral resolution CEST at 3 T

K Wang, S Park, DO Kamson, Y Li… - Magnetic resonance in …, 2023 - Wiley Online Library
Purpose To extract guanidinium (Guan) and amide CEST on the human brain at 3 T MRI
with the high spectral resolution (HSR) CEST combined with the polynomial Lorentzian line …

Magnetic resonance imaging and spectroscopy methods to study hepatic glucose metabolism and their applications in the healthy and diabetic liver

A Gursan, JJ Prompers - Metabolites, 2022 - mdpi.com
The liver plays an important role in whole-body glucose homeostasis by taking up glucose
from and releasing glucose into the blood circulation. In the postprandial state, excess …

Visualizing subcellular enrichment of glycogen in live cancer cells by stimulated Raman scattering

D Lee, J Du, R Yu, Y Su, JR Heath, L Wei - Analytical chemistry, 2020 - ACS Publications
Glycogen, a branched glucose polymer, helps regulate glucose homeostasis through
immediate storage and release of glucose. Reprogramming of glycogen metabolism has …