Determining out-of-field doses and second cancer risk from proton therapy in young patients—an overview

M Romero-Expósito, I Toma-Dasu, A Dasu - Frontiers in Oncology, 2022 - frontiersin.org
Proton therapy has the potential to provide survival and tumor control outcomes comparable
and frequently superior to photon therapy. This has led to a significant concern in the …

Clinical commissioning of intensity‐modulated proton therapy systems: report of AAPM Task Group 185

JB Farr, MF Moyers, CE Allgower, M Bues… - Medical …, 2021 - Wiley Online Library
Proton therapy is an expanding radiotherapy modality in the United States and worldwide.
With the number of proton therapy centers treating patients increasing, so does the need for …

Second tumor risk in children treated with proton therapy

DJ Indelicato, JE Bates, RB Mailhot Vega… - Pediatric Blood & …, 2021 - Wiley Online Library
Background Out‐of‐field neutron dissemination during double‐scattered proton therapy has
raised concerns of increased second malignancies, disproportionally affecting pediatric …

Radiotherapy advances in pediatric neuro-oncology

EB Ludmir, DR Grosshans, KD Woodhouse - Bioengineering, 2018 - mdpi.com
Radiation therapy (RT) represents an integral component in the treatment of many pediatric
brain tumors. Multiple advances have emerged within pediatric radiation oncology that aim …

Patterns of proton therapy use in pediatric cancer management in 2016: an international survey

N Journy, DJ Indelicato, DR Withrow, T Akimoto… - Radiotherapy and …, 2019 - Elsevier
Purpose To facilitate the initiation of observational studies on late effects of proton therapy in
pediatric patients, we report on current patterns of proton therapy use worldwide in patients …

Impact of spot size and beam-shaping devices on the treatment plan quality for pencil beam scanning proton therapy

M Moteabbed, TI Yock, N Depauw, TM Madden… - International Journal of …, 2016 - Elsevier
Purpose This study aimed to assess the clinical impact of spot size and the addition of
apertures and range compensators on the treatment quality of pencil beam scanning (PBS) …

A study of lateral fall-off (penumbra) optimisation for pencil beam scanning (PBS) proton therapy

C Winterhalter, A Lomax, D Oxley… - Physics in Medicine & …, 2018 - iopscience.iop.org
The lateral fall-off is crucial for sparing organs at risk in proton therapy. It is therefore of high
importance to minimize the penumbra for pencil beam scanning (PBS). Three optimisation …

Evaluation and second check of a commercial Monte Carlo dose engine for small‐field apertures in pencil beam scanning proton therapy

J Holmes, J Shen, J Shan, CL Patrick… - Medical …, 2022 - Wiley Online Library
Purpose To evaluate the accuracy of the RayStation Monte Carlo dose engine (RayStation
MC) in modeling small‐field block apertures in proton pencil beam scanning. Furthermore …

Modelling small block aperture in an in-house developed GPU-accelerated Monte Carlo-based dose engine for pencil beam scanning proton therapy

H Feng, JM Holmes, SA Vora, JB Stoker… - Physics in Medicine …, 2024 - iopscience.iop.org
Purpose. To enhance an in-house graphic-processing-unit accelerated virtual particle (VP)-
based Monte Carlo (MC) proton dose engine (VPMC) to model aperture blocks in both dose …

Out-of-field doses produced by a proton scanning beam inside pediatric anthropomorphic phantoms and their comparison with different photon modalities

Ž Knežević, L Stolarczyk, I Ambrožová… - Frontiers in …, 2022 - frontiersin.org
Since 2010, EURADOS Working Group 9 (Radiation Dosimetry in Radiotherapy) has been
involved in the investigation of secondary and scattered radiation doses in X-ray and proton …