237 Drug-induced pruritus pruritus, neuronal storage of the substance evokes pruritus,
which slowly relieves after degradation of the substance. This can be grouped as chronic …

The risk‐benefit ratio associated with the use of repurposed drugs to treat severe acute
respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2)‐related infectious coronavirus disease …

Chloroquine has been used for many decades in the prophylaxis and treatment of malaria. It
is metabolized in humans through the N-dealkylation pathway, to desethylchloroquine …

One approach to investigate if human genetic variation influences the selection of
Plasmodium falciparum drug resistance is to compare the frequency of resistant infections …

Chloroquine (CQ) and Hydroxychloroquine (HCQ), initially utilized in the treatment of
malaria, have now developed a long list of applications. Despite their clinical relevance …

Chloroquine (CQ) is an antimalarial drug that elicits severe pruritus in black Africans with
malaria fever. This acute itching (2–7 days duration) exhibits age dependency and a racial …

Background The predominance of chloroquine-susceptible falciparum malaria in Malawi
more than a decade after chloroquine's withdrawal permits contemplation of re-introducing …

Aims Chloroquine induces a severe generalized pruritus, in predisposed Black African
patients, during treatment of malaria fever, and also in some Caucasian patients treated for …

Objective To determine the relative risk of drug-induced Long QT Syndrome (LQTS)
associated with SARS-CoV-2 (COVID-19) proposed repurposed drugs compared to well …

The significance of a pharmacokinetics basis in chloroquine (CQ)-induced pruritus was
investigated by determining the disposition of the drug in two groups of volunteers; pruritus …